一例复杂性泌尿系感染伴念珠菌尿患儿治疗方案分析

Analysis of Therapeutic Regimen for One Child with Complicated Urinary Tract Infection and Candiduria

目的分析药师参与的儿童复杂尿路感染伴念珠菌尿的治疗实例,促进抗感染药物合理使用及探讨酸碱化尿液临床意义。方法药师参与难治性儿童泌尿系感染伴念珠菌尿病例治疗,分析治疗过程,并对临床常用的尿液酸碱化意义进行文献检索总结。结果药师对部分抗感染方案给出建议获得采纳后治疗取得进展。针对尿液酸碱化对尿路感染治疗的临床意义提出自己的观点,不再支持碱化尿液辅助治疗念珠菌性尿路感染。结论药师参与临床治疗有助于治疗方案改进,通过文献可为临床合理用药提供参考,纠正不良用药习惯。

Objective To promote the rational use of anti-infective drugs in urinary tract infection and discuss the clinical significance of urine pH change by analyzing the treatment case on a child with complicated urinary tract infection and candiduria participated by pharmacist. Methods The treatment process participated by pharmacist was retrospectively analyzed, and the clinical significance of urine pH change was probed through literature retrieval. Results Some of pharmacist＇s recommendations were adopted and the treatment outcome was advanced. The pharmacist proposed personal opinion on clinical significance of urine pH change in the treatment of urinary tract infection, no longer supported urine alkalization as auxiliary treatment to candidal urinary tract infections. Conclusion Pharmacist＇s participating in treatment can contribute to clinical outcome, and correct drug-using habit through evidence-based literature.