依帕司他治疗糖尿病周围神经病变有效性和安全性的临床研究

Epalrestat Diabetic Peripheral Clinical Efficacy and Safety Studies Neuropathy Treatment

目的研究依帕司他治疗糖尿病周围神经病变临床治疗的有效性和安全性。方法随机取2014年1月—2015年12月该院收治的82例2型糖尿病周围神经病变患者,把82例患者分成对照组与观察组,分别应用甲钴胺和依帕司他治疗,比较两组临床治疗安全性。结果观察组疗效优于对照组,两组均无严重不良反应发生。结论应用依帕司他治疗糖尿病周围神经病变效果理想,临床治疗安全性高。

Objective To study the efficacy and safety of epalrestat therapy in the treatment of diabetic peripheral neuropathy. Methods 82 cases of type 2 diabetic patients with peripheral neuropathy with, the 82 patients were divided into the control group and the observation group, respectively, and the application of methylcobalamin and epalrestat orlistat treatment, compared two groups of clinical efficacy and safety. Results The efficacy of the observation group was better than that of the control group, the two groups were no serious adverse reactions occurred. Conclusion The application of epalrestat in treatment of diabetic peripheral neuropathy with ideal effect, high safety and clinical treatment.