我院门诊围绝经期女性激素用药分析

Analysis of Utilization of Hormone Drugs in Perimenopausal Women in Outpatient of Our Hospital

目的评价我院门诊围绝经期女性激素替代治疗药物的应用现状和相关问题。方法采用回顾性分析,对我院2013年第一季度门诊围绝经期女性激素治疗药物的应用品种、销售金额、用药频度(DDDs)、日均费用(DDC)等进行统计、分析。结果我院2月份门诊围绝经期女性患者激素用药销售金额、药品销售总金额及销售金额占药品销售总金额的比例均较低,各月份中,达芙通、克龄蒙、补佳乐和利维爱的销售金额、构成比始终居于前列,补佳乐所用比例呈逐月上升趋势,利维爱逐月下降。各月份中,补佳乐、克龄蒙、达芙通和欧维婷的使用频率始终处于前列,在各月份的DDC排序中,益玛欣和达芙通始终居高不下,利维爱也相对较高。结论补佳乐、克龄蒙、达芙通和欧维婷是我院围绝经期女性激素替代治疗的常用药物,益玛欣和达芙通这两种药物对患者的经济负担较重。

Objective To evaluate the status and issues of drugs related to hormone replacement therapy（HRT） in perimenopausal women in outpatient of our hospital. Methods The utilization of drugs related to HRT in perimenopausal women in outpatient of our hospital in the fi rst quarter of 2013 was analyzed retrospectively in terms of varieties, consumption sum, DDDs, DDC, etc. Results The consumption sum of homone drugs in perimenopausal women, the total consumption sum and the ratio of the former to the latter in February 2013 were all lower. Duphaston, Climen, Progynova and Livial steadily dominated the fi rst place on the consumption and constituent ratio lists in every month. The constituent ratio of Progynova showed an upward trend by month, while Livial was downward. Progynova, Climen, Duphaston and Ovestin were always on the top of the DDDs list in all months. In terms of DDC, Progesterone capsules and Duphaston ranked at the top 2 places in each month, followed by Livial. Conclusion Progynova, Climen, Duphaston and Ovestin were general drugs for HRT in perimenopausal women in our hospital. Progesterone capsules and Duphaston might be the heavy economic burden of patients.