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转录因子及转录后调控因子参与耐药性癫痫形成的机制

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摘要 癫痫为一种慢性脑部疾病,是由大脑神经元反复异常同步化放电所致的发作性运动、感觉、意识、精神以及植物神经功能异常。癫痫可由累及脑部的突发事件如外伤、感染、肿瘤等所致,也可由调控大脑兴奋性的离子通道、神经递质的基因突变所致。全球约有占世界总人数1%的近6500万人口饱受着癫痫折磨。
出处 《癫痫与神经电生理学杂志》 2016年第3期154-159,共6页 Journal of Epileptology and Electroneurophysiology(China)
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