1990年与2013年中国人群肺癌疾病负担分析

Disease burden of lung cancer in the Chinese population, in 1990 and 2013

目的分析1990年与2013年中国人群归因于肺癌的疾病负担。方法利用2013年全球疾病负担研究结果，采用死亡率、过早死亡损失寿命年（YLL）、伤残损失寿命年（YLD）和伤残调整寿命年（DALY）等指标，对中国人群肺癌的疾病负担情况进行描述，并通过计算1990年与2013年相应指标的变化幅度，描述全国肺癌疾病负担的变化情况。结果中国人群肺癌的标化死亡率从1990年的36．04／10万增至2013年的40．41／10万，增加12．13％，标化YLL率从1990年的805．07／10万降至2013年的781．09／10万，降低2．98％；标化YLD率从1990年的8．57／10万升至2013年的11．13／10万，增加29．87％；标化DALY率从1990年的813．64／10万降至2013年的792．22／10万，降低2．63％。与1990年相比，中国人群肺癌的死亡数、YLL、YLD和DALY值均显著上升，且男性上升幅度均比女性大。男性和女性的肺癌死亡率和DALY率均随年龄增加呈上升趋势，且每个年龄段的男性死亡率和DALY率均明显高于女性。东北、华北地区，西南的四川、重庆及部分东中部地区2013年肺癌的标化死亡率和DALY标化率明显高于其他地区，西部地区相对较低。结论与1990年相比，2013年中国人群肺癌死亡造成的疾病负担仍较为严重，各省份肺癌造成的疾病负担水平各有差异，针对相关危险因素开展有针对性的防控措施十分重要。

[Abstract] Objective To analyze the disease burden of lung cancer in the Chinese population, in 1990 and 2013. Methods Indicators including mortality rate, years of life lost due to premature mortality （YLL）, years lived with disability （YLD）, and disability-adjusted of life years （DALY） on lung cancer, were from the results of Global Burden of Disease （GBD） 2013 and were used to describe the burden of disease caused by lung cancer in the Chinese population. Data described the disease burden of lung cancer in China by calculating the changing rates on corresponding parameters in 1990 and 2013. Results In China, in 1990 and 2013, the standardized mortality rate of lung cancer increased from 36.04/100 000 to 40.41/100 000 （increased by 12.13%）, the standardized YLL rate decreased from 805.07/100 000 to 781.09/100 000 （decreased by 2.98%）, the standardized YLD rate increased from 8.57/100 000 to 11.13/100 000 （increased by 29.87%） and the standardized DALY rate decreased from 813.64/100 000 to 792.22/100 000 （decreased by 2.63%）. Compared with data in 1990,parameters as the number of deaths, YLL, YLD and DALY of lung cancer all increased, especially in males. Mortality and the DALY rate of lung cancer increased with age in both genders. Mortality and DALY rate were higher in males than those in females in all the age groups. Geographically, standard mortality rate and standard DALY rate in northeast region, north region, southwest region （Sichuan and Chongqing） and part of the east and central regions appeared significantly higher than those in other regions but lower in western region than those in other regions, in 2013. Conclusions Burden of disease caused by lung cancer remained serious in China. Provincially, the burden of disease caused by lung cancer appeared different. It is important to strengthen the prevention and control programs that related to lung cancer.