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化学交换饱和转移磁共振成像技术测定肿瘤细胞外pH的研究进展 被引量:1

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摘要 肿瘤组织酸碱度下降是由于肿瘤组织糖代谢紊乱,以及组织低灌注的结果,精确的测定肿瘤组织内环境的酸碱度对于诊断肿瘤恶性程度、转移概率及检测化疗效能有着重要的作用。近年来,使用磁共振分子影像技术测定组织酸碱度的研究取得较大进展,并已开始应用于临床。为此,笔者综述了化学交换饱和转移磁共振成像技术,以及其在测定肿瘤细胞外酸碱度的应用和研究进展,并探讨其相对于其他成像方式的优点以及前景。
出处 《功能与分子医学影像学(电子版)》 2016年第1期57-60,共4页 Functional and Molecular Medical Imaging(Electronic Edition)
基金 国家自然科学基金(81471730)
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