高容量血液滤过治疗时机对老年感染性休克患者预后的影响

The Effect of High Volume Hemofiltration Treatment Time on Elderly Patients with Septic Shock Prognosis

目的:探讨高容量血液滤过治疗时机对老年感染性休克患者预后的影响。方法:选取本院从2013年8月-2015年6月ICU治疗的42例老年感染性休克患者为研究对象。按照入院顺序随机分为观察组与对照组,每组各21例。观察组患者在早期复苏6 h内联合高容量血液滤过治疗,对照组患者在早期复苏6 h后给予高容量血液滤过治疗。比较两组患者不同治疗时机应用高容量血液滤过治疗对其预后的影响。结果:观察组患者治疗后各器官功能改善情况优于对照组患者,两组比较差异均有统计学意义(P<0.05)。观察组患者治疗后APACHEⅡ评分及MODS评分改善情况优于对照组,两组比较差异均有统计学意义(P<0.05)。观察组患者治疗后血清炎症指标改善情况优于对照组,两组比较差异均有统计学意义(P<0.05)。结论:对老年感染性休克患者在早期复苏6 h内联合高容量血液滤过治疗,器官功能恢复效果显著,预后良好,死亡率较低,值得临床广泛推广应用。

Objective：To investigate the effect of high-capacity treatment time hemofiltration on elderly patients with septic shock prognosis.Method：42 elderly patients with septic shock in our hospital of ICU treatment were selected from August 2013 to June 2015 as research objects.According to admission,they were randomly divided into two groups,21 cases in each group.The observation group was combined with high volume hemofiltration in early recovery 6 h treatment,control group was given high volume hemofiltration treatment after early recovery 6 h.The effects of different timing high volume hemofiltration treatment of two groups were compared.Result：After treatment,the various organ function of observation group were better than control group,the differences were statistically significant（P0.05）;the APACHEⅡ scores and MODS scores of observation group were better than control group,the differences were statistically significant（P0.05）;the serum inflammatory markers of observation group were better than control group,the differences were statistically significant（P0.05）.Conclusion：The elderly patients with septic shock in the early recovery 6 h joint high-volume hemofiltration,organ function recovery effect is significant,the prognosis is good and lower mortality,it is worth widely application.