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观察缬沙坦和贝那普利联合应用治疗糖尿病肾病的临床疗效

To Observe the Clinical Effect of Valsartan Combined with Benner Pury in the Treatment of Diabetic Nephropathy
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摘要 目的观察缬沙坦与贝那普利联合在糖尿病肾病治疗中的临床疗效。方法将在该院进行治疗的糖尿病肾病患者50例作为研究对象,应用数字随机法将其分为对照组与治疗组,对照组的患者应用缬沙坦进行单独治疗,治疗组的患者应用缬沙坦联合贝那普利联合治疗,对比分析两组患者治疗后的尿蛋白排泄率、平均血压。结果治疗组患者的临床治疗总有效率明显优于对照组(P<0.05),在临床各项检测指标方面也明显优于对照组(P<0.05)。结论应用缬沙坦联合贝那普利对糖尿病肾病进行治疗,能够有效的改善患者血压,在降低患者尿蛋白方面具有显著的效果,临床疗效显著,值得在糖尿病肾病的临床治疗中进行推广应用。 Objective To observe the clinical effects of valsartan and benazepril combined with in the treatment of diabetic nephropathy. Methods In our hospital were treated diabetic nephropathy patients with 50 cases as the research object, by random number method will be divided into the control group and the treatment group. in the control group the patients were treated with valsartan separate treatment, treatment group treated with valsartan combined with benazepril combined treatment, comparative analysis of two groups of patients after urinary albumin excretion rate, average blood pressure. Re-sults Treatment group, the clinical treatment total efficiency is obviously superior to the control group (P〈0.05) in the clini-cal examination Measuring index is significantly superior to the control group (P〈0.05). Conclusion Application of valsartan combined with benazepril on diabetic nephropathy treatment, can effectively improve the patient's blood pressure, showed a significant effect in reducing proteinuria in patients with, clinical curative effect is remarkable, it is worth popularization and application in the clinical treatment of diabetic nephropathy.
作者 索秀芳
出处 《糖尿病新世界》 2016年第8期25-26,共2页 Diabetes New World Magazine
关键词 糖尿病肾病 缬沙坦 贝那普利 临床疗效 Diabetic nephropathy Valsartan Benazepril Clinical efficacy
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  • 1史燕涛.卡托普利临床应用及进展[J].中国中医药现代远程教育,2009,7(4):70-71. 被引量:12
  • 2倪杰,徐鹏,张均,张龙,房宇.骨化三醇联合福辛普利治疗2型糖尿病肾病的临床观察[J].实用老年医学,2013,27(2):119-122. 被引量:7
  • 3王成,娄探奇,唐骅,彭晖,刘迅,游宇平,陈珠江,余学清.双重阻断肾素-血管紧张素系统对慢性肾脏疾病血压、蛋白尿和肾功能的影响[J].中华肾脏病杂志,2006,22(7):398-401. 被引量:35
  • 4Acourciere Y, Beanger A. Long-term comparison of valsartan and enalapril on kidney function in hypertensive type 2 diabetics with early nephropathy ( J ). Kidney Int,2000 ;58 (2) :762.
  • 5王海燕 郑法雷 刘玉春 等.原发性肾小球疾病分型与治疗及诊断标准专题座谈会纪要,慢性肾衰诊断标准及分期.中华内科杂志,1993,32(2):131-134.
  • 6Felício JS,de Souza AC,Kohlmann N,et al.Nocturnal blood pressure fall as predictor of diabetic nephropathy in hypertensive patients with type 2 diabetes[J].Cardiovasc Diabetol,2010,9:36.
  • 7K. Schjoedt,P. Jacobsen,K. Rossing,F. Boomsma,H. Parving.Dual Blockade of the Renin-angiotensin-aldosterone System in Diabetic Nephropathy: The Role of Aldosterone[J]. Horm Metab Res . 2005 (S 1)
  • 8王远英,孙承美.ARB的肾保护作用机制和临床应用研究进展[J].中国医药导报,2007,4(12S):27-28. 被引量:15
  • 9Xu Y, Wang L, He J, Bi Y, Li M, Wang T, et al. Prevalence and control of diabetes in Chinese adults. JAMA2013;310:948-59.
  • 10Zuo L, Wang M, Chinese Association of Blood Purification Management ofChinese Hospital Association. Current burden and probable increasing incidence of ESRD in China. Clin Nephrol 2010;74 Suppl 1 :S20-2.

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