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术毕前静注地佐辛对妇科腹腔镜手术后复苏期及术后疼痛的影响 被引量:4

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摘要 目的观察术毕前应用地佐辛对妇科腹腔镜手术患者术后复苏的影响及对术后疼痛干预效果。方法将择期行腹腔镜下行妇科手术的60例患者纳入研究,ASAⅠ-Ⅱ级,随机分为观察组和对照组,每组30例。两组麻醉方法相同,观察组术毕前30-40min静脉注射地佐辛0.1mg/kg(生理盐水稀释至10ml),对照组注射同容量生理盐水。记录两组患者诱导前、注药后及苏醒前、后的MAP、HR变化,苏醒后30min及1h、2h、4h的VAS和RASS评分,以及不良反应。结果两组患者恢复自主呼吸时间、苏醒期PO2、PCO2、Sa O2水平比较差异均无统计学意义(P>0.05);观察组的每个时点的RASS和VAS评分均明显低于对照组(P<0.05);对照组的1h、2h、4h等时点的RASS和VAS评分均明显低于30min时点的评分。对照组需注射曲马朵的患者明显多于观察组(P<0.05);观察组发生寒战比例明显低于对照组(P<0.05);两组恶心、呕吐发生率无显著差异(P>0.05)。结论妇科腹腔镜术毕前静脉注射地佐辛,能有效减轻妇科术后疼痛,血液动力学稳定,对呼吸无明显抑制,寒战发生率低,不增加恶心、呕吐的发生率,值得推广。
出处 《江西医药》 CAS 2016年第5期461-463,共3页 Jiangxi Medical Journal
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