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21基因在激素受体和淋巴结阳性早期乳腺癌治疗决策中的地位 被引量:1

Value of 21-gene Assay in Treatment Decisions for Hormone Receptor-positive Nodepositive Early Breast Cancer
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摘要 随着乳腺癌早期诊断率的逐步提高,对激素受体阳性、淋巴结阴性的乳腺癌患者,运用21基因复发风险评分来决策治疗,已逐步被临床医师所接受,但其在激素受体阳性、淋巴结阳性的早期乳腺癌治疗中的地位仍在不断地探讨中。本文将通过对几个临床研究结果的分析,来阐述激素受体阳性、腋窝淋巴结阳性的早期乳腺癌复发评分结果对治疗决策的意义。 With the recently increasing number of the women newly diagnosed with early breast cancer(EBC), the 21-gene recurrence score assay has been clinically validated and recommended for the treatment decisionmaking in patients with ER(+), node-negative(N0) EBC. A growing body of evidence from several large phase Ⅲ clinical trials reports similar findings in patients with ER(+), N(+) EBC. This assay could help guide treatment decisions for the patients who are most likely to receive benefit from chemotherapy.
作者 莫文菊 俞洋
出处 《肿瘤防治研究》 CAS CSCD 北大核心 2016年第6期534-537,共4页 Cancer Research on Prevention and Treatment
关键词 乳腺癌 21基因复发风险评分 预后 Breast cancer 21-gene recurrence score Prognosis
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