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糖尿病肾病的研究进展 被引量:40

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摘要 糖尿病肾病(DN)是糖尿病微血管病变的严重并发症,是当前终末期肾病(ESRD)的主要原因。美国新诊断的ESRD中DN占44%,中国由DN所致的ESRD正逐年上升,迫切需要有效的措施来预防和延缓DN的发生和发展。DN是病理诊断,传统是指糖尿病所合并的肾小球硬化症,表现为典型的系膜区增生、肾小球基底膜的增厚以及肾小球硬化。
出处 《临床内科杂志》 CAS 2016年第5期296-299,共4页 Journal of Clinical Internal Medicine
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  • 1Boer I HD, Rue TC, Cleary PA, et al. Long-term renal outcomes of patients with type 1 diabetes mellitus and microalbuminuria:an analysis of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications cohort[ J]. Arch Intern Med, 2011,171 (5) :412-420.
  • 2Pavkov ME, Knowler WC, Bennett PH, et al. Increasing incidence of proteinuria and declining incidence of end-stage renal disease in diabetic Pima Indians[ J]. Kidney Int ,2006,70 (10) : 1840-1846.
  • 3Stanton RC. Clinical challenges in diagnosis and management of diabetic kidney disease[J]. Am J Kidney Dis,2014,63(2 Suppl 2) :s3-21.
  • 4Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications ( DCCT/EDIC ) Research Group, Nathan DM, Zinman B, et al. Modern-day clinical course of type 1 diabetes mellitus after 30 years ' duration: the diabetes control and complications trial/epidemiology of diabetes interventions and complications and Pittsburgh epidemiology of diabetes complications experience( 1983-2005 ) [ J]. Arch Intern Med ,2009,169 ( 14 ) : 1307-1316.
  • 5Perkins BA FLH, Roshan B,et al. In patients with type 1 diabetes and new-onsetmicroalbuminuria the development of advanced chronic kidney disease may not require progression to proteinuria [ J ]. Kidney Int ,2010,77 ( 1 ) :57-64.
  • 6Pezzolesi MG, Jan S, Mychaleckyj JC, et al. Insights to the genetics of diabetic nephropathy through a genome-wide association study of the GoKinD collection[ J]. Semin Nephrol,2010,30(2) : 126-140.
  • 7Mcdonough CW, Palmer ND, Hicks PJ, et al. A genome-wide association study for diabetic nephropathy genes in Mrican Americans[J]. Kidney Int,2011,79(5) :563-572.
  • 8Brorsson C, Pociot F. Genetics of diabetic nephropathy in diverse ethnic groups[ J]. Contrib Nephre1,2011,170:8-18.
  • 9Vasylyeva TL, Chen X, Ferry RJJr. Insulin-like growth factor binding protein-3 mediates cytokine-induced mesangial cell apoptosis [ J ]. Growth Horm IGF Res,2005,15 (3) :207-214.
  • 10Lin CL, Wang JY, Huang YT, et al. Wnt/beta-catenin signaling modulates survival of high glucose-stressed mesangial cells [ J ]. J Am Soc Nephrol,2006,17 (10) :2812-2820.

二级参考文献79

  • 1李春媚,刘素雁,阮颖新,赵钰,朱兆杰,隋满姝.卡维地洛改善顺铂致肾小管上皮细胞凋亡[J].中华肾脏病杂志,2006,22(11):677-681. 被引量:2
  • 2蒋素华,丁小强,张晓丽,许迅辉,何广成,刘春凤,陈越.急性缺血再灌注损伤对肾脏的近期和远期作用[J].中华肾脏病杂志,2007,23(4):246-250. 被引量:4
  • 3Brownlee M.Biochemistry and molecular cell biology of diabetic complications.Nature,2001,414:813-820.
  • 4Lowell BB,Shulman GI.Mitochondrial dysfunction and type 2 diabetes.Science,2005,307:384-387.
  • 5Westermann B.Mitochondrial fusion and fission in cell life and death.Nat Rev Mol Cell Biol,2010,11:872-884.
  • 6Cho DH,Nakamum T,Fang J,et al.S-nitrosylation of Drpl mediates beta-amyloid-related mitochondrial fission and neuronal injury.Science,2009,324:102-105.
  • 7Okamoto K,Shaw JM.Mitochondrial morphology and dynamics in yeast and multicellular eukaryotes.Annu Rev Genet,2005,39:503-536.
  • 8Wang W,Fang H,Groom L,et al.Superoxide flashes in single mitochondria.Cell,2008,134:279-290.
  • 9Danial NN,Korsmeyer SJ.Cell death:critical control points.Cell,2004,116:205-219.
  • 10Suen DF,Norris KL,Youte RJ.Mitochondrial dynamics and apoptosis.Genes Dev,2008,22:1577-1590.

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