2型糖尿病患者住院期间体重变化的临床分析

The clinical analysis of the weight changes in type 2 diabetes mellitus inpatients

目的通过观察2型糖尿病患者住院期间的体重变化情况，探讨其体重增加的危险因素。方法测定812例2型糖尿病患者入院次日及出院当天体重，并收集相关临床资料，对住院期间体重变化及相关因素进行统计分析。结果大部分2型糖尿病患者住院期间体重发生明显变化，其中体重增加者为54．1％，体重减少者为18．5％，27．4％体重无明显变化。与体重减轻组及体重不变组相比，体重增加组年龄较小（P〈0．05）、初诊断者及入院前体重下降者比例高（P均〈0．01）、体重减轻组使用百泌达比例较体重增加组和体重不变组明显升高（P〈0．01）。结论2型糖尿病住院期间体重变化是普遍现象，其中体重增加较为突出，且与年龄小、初诊断、使用胰岛素及入院前体重下降相关。

Objective To observe the weight changes of hospitalized patients with type 2 diabetes and explore the risk factors for weight gain. Methods Weights of 812 cases of diabetic inpatients were measured on the second day in hospital and the day of discharge. The clinical data were collected as well as the correlation between weight change and related clinical factors were analyzed. Results Most of the diabetic inpatients had a significant change in body weight,54.1% of them gained weight, 18.5% lost weight and 27.4% had no significant change. Compared with the control group（ weight loss and no weight change group）, the average age of the patients in weight gaining group was younger （ P 〈 0.05 ）, the proportion of weight loss before admission and initial diagnosis were higher（P 〈 0.01 ）. Besides, Byetta could significantly increase the proportion of patients losing weight（P 〈 0.01 ）. Conclusion The change of body weight in diabetic inpatients is a common phenomenon, and the weight gain is more prominent which is related to age, initial diagnosis, using of insulin, and the weight loss before admission.