新疆和田维、汉族慢性牙周炎患者龈下菌斑中3种可疑致病菌的分布

Distribution of 3 periodontal pathogens in dental plaque with chronic periodontitis between the Uighur and Han in Hetian of Xinjiang

目的分析新疆和田维吾尔族和汉族慢性牙周炎患者龈下菌斑中不同牙周致病菌的分布情况。方法选择慢性牙周炎患者124例,维吾尔族80例,汉族44例,采集龈下菌斑,用16sRNA PCR方法检测牙龈卟啉单胞菌、福赛坦氏菌和中间普氏菌的分布。结果新疆和田维吾尔族、汉族慢性牙周炎患者龈下菌斑中牙龈卟啉单胞菌、福赛坦氏菌和中间普氏菌的检出率分别为25.0%、60.0%、50.0%和43.2%、93.2%、52.3%,维吾尔族、汉族患者牙龈卟啉单胞菌、福赛坦氏菌的检出率差异具有统计学意义(P<0.05)。新疆和田不同性别慢性牙周炎患者龈下菌斑中3种可疑致病菌的检出率差异无统计学意义(P均>0.05)。结论新疆和田维吾尔族和汉族慢性牙周炎患者龈下菌斑中牙周致病菌的分布不同,但福赛坦氏菌在维、汉族慢性牙周炎患者龈下菌斑中均为优势菌。

Objective To analysis the distribution of 3periodontal pathogens from the subgingival plaque with chronic periodontitis（CP）between Uighur and Han in Hetian of Xinjiang.Methods Subgingival plaque samples were collected from 80 Uighur CP patients and 44 Han CP patients in Hetian.Three periodontal pathogens：Porphyromonas gingivalis（P.gingivalis）,Tannerella forsythia（T.forsythia）and Prevotella intermedia（P.intermedia）were detected by 16 SrRNA polymerase chain reaction.Results The detectable rate of the Uighur and Han about P.gingivalis,T.Forsythensis and P.Intermedia were 25%,60%,50% and 43.2%,93.2%,52.3%respectively,in which the detectable rates of P.Gingivalis and T.Forsythensis have statistical differences between Uighur and Han（P〈0.05）.Conclusion The three periodontal pathogens in Uighur and Han who lived in Hetian were different distribution,and T.Forsythensis was the predominant bacteria in subgingival plaque both in Uighur and Han of Hetian.