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Genome Editing:From Drosophila to Non-Model Insects and Beyond 被引量:1

Genome Editing:From Drosophila to Non-Model Insects and Beyond
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摘要 Insect is the largest group of animals on land.Many insect species inflict economical and health losses to humans.Yet many more benefit us by helping to maintain balances in our ecosystem.The benefits that insects offer remain largely untapped,justifying our continuing efforts to develop tools to better understand their biology and to better manage their activities.Here we focus on reviewing the progresses made in the development of genome engineering tools for model insects.Instead of detailed descriptions of the molecular mechanisms underlying each technical advance,we focus our discussion on the logistics for implementing similar tools in non-model insects.Since none of the tools were developed specific for insects,similar approaches can be applied to other non-model organisms. Insect is the largest group of animals on land.Many insect species inflict economical and health losses to humans.Yet many more benefit us by helping to maintain balances in our ecosystem.The benefits that insects offer remain largely untapped,justifying our continuing efforts to develop tools to better understand their biology and to better manage their activities.Here we focus on reviewing the progresses made in the development of genome engineering tools for model insects.Instead of detailed descriptions of the molecular mechanisms underlying each technical advance,we focus our discussion on the logistics for implementing similar tools in non-model insects.Since none of the tools were developed specific for insects,similar approaches can be applied to other non-model organisms.
出处 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2016年第5期263-272,共10页 遗传学报(英文版)
基金 supported by a grant from the National Natural Science Foundation of China(No.NSFC #31371364)
关键词 Insect transgenesis Drosophila Black soldier fly Gene targeting Site-specific recombination Piggybac transposon Insect transgenesis Drosophila Black soldier fly Gene targeting Site-specific recombination Piggybac transposon
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