中性粒细胞与淋巴细胞比值对介入治疗后急性心肌梗死患者预后的影响被引量：6

Effects of neutrophil and lymphocyte ratio on the prognosis of patients with acute myocardial infarction after percutaneous coronary intervention

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摘要目的探讨中性粒细胞与淋巴细胞比值（neutrophil and lymphocyte ratio,NLR）对经皮冠状动脉介入治疗（percutaneous coronary intervention,PCI）后急性ST段抬高型心肌梗死（acute ST segment elevation myocardial infarction,STEMI）患者预后的影响。方法选取2009年1月~2014年11月急性ST段抬高型心肌梗死行急诊PCI的患者300例,依据入院时NLR值将其分为两组（A组NLR〉3.30,B组NLR≤3.30）,对两组患者心功能相关指标（NT-Pro BNP水平、射血分数）、ST段回落情况、心肌酶学指标、室性心律失常及住院期间主要心血管事件（major cardiovascular events,MACE）发生情况进行比较。结果与NLR〉3.30患者相比,NLR≤3.30患者PCI术后心电图ST段在术后早期即明显回落,术中及术后恶性室性心律失常的发生率明显降低（P〈0.05）。术后12 h内CK-MB水平较NLR〉3.30组明显降低（P〈0.05）。NLR≤3.30患者心功能恢复情况较好（P〈0.05）。结论中性粒细胞与淋巴细胞比值对PCI术后急性ST段抬高型心肌梗死患者的病情评估及预后判断有重要指导意义。 Objective To investigate the effects of neutrophil and lymphocyte ratio（NLR） on the prognosis of patients with acute ST segment elevation myocardial infarction（SETMI） after percutaneous coronary intervention（PCI）.Methods all 300 patients with SETMI who received PCI from January 2009 to November 2014 were selected and divided into two groups based on the NLR upon admission（group A：NLR 3.30;group B：NLR≤3.30）.The cardiac function indexes（NT-Pro BNP level,ejection fraction）,ST segment resolution,myocardial zymetology,ventricular arrhythmias and major cardiovascular events（MACE） during hospitalization of the patients from both groups were compared.Results Compared to patients with NLR 3.30,obvious ST segment resolution were shown in the patients with NLR≤3.30 soon after the PCI and the incidence rate of malignant ventricular arrhythmias during and after the PCI was decreased significantly（P〈0.05）.The CK-MB level within 12 hours after PCI of patients with NLR ≤3.30 was decreased significantly compared with patients with NLR3.30（P〈0.05）.The recovery of cardiac function of patients with NLR ≤3.30 was better（P〈0.05）.Conclusion NLR has important guiding significance on the disease evaluation and prognosis of patients with SETMI after PCI.

作者吕常智

机构地区辽宁省丹东市第一医院心血管内科

出处《中国现代医生》 2016年第12期1-3,7,共4页 China Modern Doctor

关键词中性粒细胞与淋巴细胞比值心肌梗死 PCI治疗预后 Neutrophil and lymphocyte ratio Myocardial infarction PCI Prognosis

分类号 R543.3 [医药卫生—心血管疾病]

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