奥硝唑联合Vitapex治疗急性根尖周炎的临床观察

Clinical Observation of Ornidazole Combined with Vitapex in the Treatment of Acute Periapical Periodontitis

目的:探讨奥硝唑静脉滴注联合Vitapex治疗急性根尖周炎患者的临床疗效。方法:选择自2013年7月至2015年8月在本医院治疗的患者85例,随机将其分为观察组43例,对照组42例,其中,对照组给予牙周基础治疗加Vitapex根管充填治疗,观察组经上述治疗后给以滴注奥硝唑静脉。治疗后观察记录两组患者患者治疗后1周的患牙反应情况以及治疗后1月和3月的总体疗效,并进行统计分析。结果:治疗后1周,观察组的治疗后反应明显优于对照组(P<0.05);治疗后1月,观察组和对照组的总有效率分别为95.3%(41/43)和88.1%(37/42);治疗后3月,观察组和对照组的总有效率分别为97.7%(42/43)和85.7%(36/42),差异具有统计学意义(P<0.05)。结论:通过奥硝唑静脉滴注联合Vitapex治疗能明显改善AAP患者的牙患症状,疗效显著。

Objective: To investigate the clinical curative effect of ornidazole vein infusion combined with Vitapex treatment in patients with acute periapical periodontitis.Methods:85 patients with APP in this hospital since Jul 2013 to Aug 2015 were selected and randomly divided into observation group 43 cases and control group,42 cases in this study.The control group were treated with periodontal basic treatment with vitapex root canal filling while the observation group were treated with ornidazole intravenous drip treatment on the basis of the control group.The reaction of the suffering teeth 1 week after the treatment,the overall curative effect 1 and 3 months after the treatment were recorded for statistical analysis in the two groups.Results:The reaction of the suffering teeth 1 week after the treatment in the observation group were obviously better than it in the control group (P<0.05); the total efficiency of the observation group and the control group 1 month after the treatment were respectively 95.3% (41/43) and 88.1% (37/42); the total efficiency of the observation group and the control group 3 month after the treatment were respectively 97.7% (42/43) and 85.7% (36/42),the difference was statistically significant (P<0.05).Conclusion:Ornidazole combined vitapex root canal filling can significantly improve the symptoms for patients with APP with a significant effect,thus it’s worth popularization and application in clinic.