B族链球菌检测在围产期孕妇感染诊断中的意义

Screening group B streptococcus in perinatal infection： detection methods and clinical value

B族链球菌（GBS）是一种可导致围产期母胎感染的条件致病菌，与晚期流产及早产、胎膜早破、围产期感染、新生儿感染等疾病相关。美国疾病控制预防中心（CDC）防治指南建议对所有妊娠35—37周的孕妇标本进行检测。检测方法包括微生物学、免疫学、分子生物学等，可根据不同情况选择适合的方法。GBS预防性治疗首选青霉素，不适应者再根据药敏结果选择药物进行治疗。目前尚无可用于临床的疫苗，

Group B Streptococcus （GI3S） is a conditional pathogenic bacteria related to late-term abortion, premature delivery, premature rupture of membranes, perinatal infection, neonatal sepsis and other diseases. Prevention and treatment guidelines by the US Centers for Disease Control and Prevention （CDC） suggest that all the pregnant women at 35-37 gestational weeks should screen for GBS. The detection methods for GBS include microbiology, immunology, molecular biology, etc. The appropriate method should be chosen depending on circumstances. Penicillin is recommended for the preventive treatment of GBS, and the treatment for the insensitive should base on the antibiotic susceptibility results. No vaccine against GBS is currently available for clinical use.