苯磺酸氨氯地平片联合雷火灸治疗阳虚型高血压临床观察

Clinical Observation of Amlodipine Besylate in Combination with Thunder-fire Moxibustion Applied in the Hypertension with Syndrome of Yang Deficiency

目的:观察苯磺酸氨氯地平片联合雷火灸干预阳虚型高血压的临床效果。方法:采用随机对照实验,将合格患者随机分为两组,对照组患者予以口服苯磺酸氨氯地平片。观察组患者在对照组基础上联合使用雷火灸,选穴为:气海、关元、双涌泉、双足三里,分别在治疗前、治疗结束后进行随访观察。结果:合格患者70例,随访期间先后共11名患者脱落,最终纳入分析59例。血压方面,观察组患者总有效率较对照组高约10%,两组比较,差异均无统计学意义(P>0.05)。症状积分方面,观察组患者总有效率较对照组高约24%,两组比较,差异具有统计学意义(P<0.05)。结论:苯磺酸氨氯地平片联合雷火灸干预不仅能够有效降低阳虚型高血压患者的血压水平,还能改善患者整体症状。

Objective To explore the clinical efficacy of amlodipine besylate tablets in combination with thunder-fire moxibustion applied in the hypertension with syndrome of yang deficiency. Methods The eligible patients were randomly divided into two groups by randomized controlled trial, applied with 5mg oral amlodipine besylate tablets once a day for 2 months in control group. With selected acupoints： Qihai, Guan Yuan, double springs as well as double Zusanli the thunder-fire moxibustion was used in experimental group on the basis of control group. Each acupuncture point was treated with moxibustion for 15 min every time a day and 5 times were defined as a course of treatment which has a two-day interval between adjacent treatment, the full treatment lasts for 2 months. Observation were made pre and post-treatment. Results A total of 70 qualified patients including 59 cases contained in the final analysis and 11 cases fell off during the follow-up period were chose for the experiment. In terms of blood pressure, the total effective rate of the experimental group was about 10 % higher than that of the control group, but the difference was insignificant between the two groups（P 〉0.05）. With regard to the symptom score, the experimental group has a 24 % higher total effective rate with statistical significance（P〈 0.05） in comparison with the control group. Conclusion Amlodipine besylate tablets in combination with thunder-fire moxibustion not only decreased the blood pressure but improved the whole symptom in patients suffered from the hypertension with syndrome of yang deficiency.