多囊卵巢综合征合并妊娠期糖尿病孕妇孕产结局分析

Analysis on outcomes of maternal and neonatal in women with polycystic ovary syndrome and gestational diabetes mellitus

目的：探讨多囊卵巢综合征（PCOS）患者妊娠期糖尿病（GDM）的妊娠及新生儿结局。方法：选取2014年1月~2016年1月在本院进行产前检查确诊为GDM的孕妇,将符合入选标准的孕妇分为PCOS组（102例）和对照组（97例）。观察并记录两组孕妇的妊娠结局（妊娠期高血压、子痫前期、早产、羊水过多及羊水过少）及新生儿结局指标（新生儿体重、巨大胎儿、新生儿Apgar评分、新生儿黄疸、呼吸窘迫综合症及低血糖）。结果：PCOS组妊娠期高血压、子痫前期和新生儿低血糖的发生率高于对照组（P〈0.05）;两组中早产、羊水过多、羊水过少、新生儿体重、巨大胎儿、新生儿Apgar评分、新生儿黄疸及呼吸窘迫综合征等发生率比较均无统计学差异（P〉0.05）。结论：PCOS增加了GDM孕妇的妊娠期高血压、子痫前期和新生儿低血糖等患病风险,但未加重其他不良妊娠及新生儿并发症。

Objective： To explore the outcomes of patients with gestational diabetes mellitus （GDM） and polycystic o- vary syndrome （PCOS）. Method： From January 2014 to January 2016, the pregnant women diagnosed as GDM in peo pie＇s hospital of Zhengzhou were recruited and were divided into PCOS group （102 eases） and control group （97 cases）. The maternal outcomes （including Gestational hypertension, preeclampsia, premature birth, polyhydramnios and oli- gohydramnios） and neonatal outcomes （including birth weight, fetal macrosomia, neonatal Apgar score, neonatal jaundice, respiratory distress syndrome and hypoglycaemia） in the two groups were observed and analyzed. Result： The incidence of gestational hypertension, preeclampsia and neonatal hypoglycemia in PCOS group were significantly higher than those of control group （P〈0.05）. The rate of premature birth, polyhydramnios, oligohydramnios, low birth weight, fetal macrosomia, neonatal Apgar score, neonatal jaundice and respiratory distress syndrome in the two groups had no statistically significant difference （P〉0.05）. Conclusion： PCOS increase the risk of gestational hyper- tension, preeclampsia and neonatal hypoglycemia for pregnant women with GDM, but don＇t affect incidence of other adverse pregnancy or neonatal outcomes.