1Hart RG, Pearce LA, Aguilar MI. Meta-analysis : antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation[ J ]. Ann Intern Med,2007, 146: 857.
2The International Warfarin Pharmacogenetics Consortium. Estimation of the warfarin dose with clinical and pharmacogenetic data[J]. N Engl J Med, 2009, 360(8) :753.
3Gage BF,Eby C,Johnson JA, et al. Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin [ J ]. Clin Pharmacol Ther, 2008,84(3) :326.
4Rieder MJ, Refiner AP, Gage BF, et al. Effect of VKORC! haplotypes on transcriptional regulation and warfarin dose [ J ]. N Engl J Med, 2005, 352:2285.
6Zhou Q, Zhau S, Chan E. Effect of omeprazole on the hydroxylation of warfarin enantiomers in human:in-vitro studies with liver microsomes and cDNA-expressed cytochrome P450 isozymes [ J 1 . Curr Drug Metab, 2005,6(5) :399.
7Joan LR, Gerda T, Lynora S. Stability of heparin and physical compatibility of heparin/antibiotic solutions in concentrations appropriate for antibiotic lock therapy [ J ]. J Antimicro Chemoth ,2005 ,56 :951-953.
8Zhou Q, Zhou S, Chan E. Effect of omeprazole on the hydroxylation of warfarin enantiomers in human: in-vitre studies with liver microsomes and cDNA-expressed cytochrome P450 isozymes[ J]. Curr Drug Metab, 2005,6(5) : 399- 411.
9Unge P, Svedberg LE, Nordgren A. A study of the interaction of omeprazole and warfarin in anticoagulated patients [ J ]. Br J Clin Pharmacol, 1992,34 (6) :509-512.
10Sutfin T, Balmer K, Bostrom H. Stereoselective interaction of omeprazole with warfarin in healthy men[J]. Ther Drug Monit,1989,11(2) :176-184.
