佛山市均安镇流动儿童手足口病发病危险因素的病例对照研究

A case-control study on risk factors of hand-foot-mouth disease among migrant children in Jun'an Town of Foshan City

目的探讨佛山市均安镇流动儿童手足口病发生的相关危险因素,为手足口病的防控提供科学依据。方法在中国疾病预防控制信息系统中随机选择2014年1月—2015年6月报告的300例手足口病流动患儿作为病例组,并以1∶1配对方式选择300例非手足口病健康流动儿童作为对照组,分别对家长进行问卷调查,采用多因素logistic回归分析筛选手足口病发病的危险因素。结果对流动儿童手足口病危险因素单因素分析发现,儿童带养类型、手足口病患者接触史、有吮咬手指的习惯、无使用肥皂/洗手液洗手的习惯、居住地有人粪堆积现象、居住地有生活垃圾堆积现象、儿童生病频率与流动儿童手足口病的发生有关(P<0.05)。多因素logistic回归分析显示:散居儿童(OR=1.196)、手足口病接触史(OR=2.130)、有吮咬手指的习惯(OR=1.252)、居住地有人粪堆积(OR=1.986)是流动儿童手足口病发病的危险因素。结论减少和控制手足口病的危险因素是预防流动儿童手足口病发病的重要环节。

[Objective]To investigate the risk factors of hand-foot-mouth disease among migrant children in Jun＇an Town of Foshan City,provide scientific basis for prevention and control of hand-foot-mouth disease.[Methods]300 migrant children with handfoot-mouth disease,who were reported from January 2014 to June 2015,were randomly collected from the Management reporting system of the national disease surveillance information as the case group. By matching with the case group（1 ∶1）,300 healthy migrant children without hand-foot-mouth disease were enrolled in the control group. The questionnaire survey was performed among the parents,and the multivariate logistic regression was used to analyze the risk factors of hand-foot-mouth disease.[Results]Univariate analysis showed that child care type,contact history to patients of hand-foot-mouth disease,habit of sucking fingers,having no habit of washing hands with the soap/hand sanitizer,human fecal accumulation in the place of residence,life garbage accumulation in the place of residence,and frequency of illness were related to the hand-foot-mouth disease of migrant children. Multivariate logistic regression showed that scattered children（OR=1.196）,contact history of hand-foot-mouth disease（OR=2.130）,habit of sucking fingers（OR=1.252）and human fecal accumulation in the place of residence（OR=1.986）were the risk factors of hand-foot-mouth disease in migrant children.[Conclusion]To reduce and control the risk factors of hand-foot-mouth disease are the important link of preventing the hand-foot-mouth disease among migrant children.