厦门市慢性阻塞性肺疾病死亡率的影响因素

Influencing factors of mortality of chronic obstructive pulmonary disease in Xiamen City

目的探讨厦门市慢性阻塞性肺疾病(COPD)死亡率的影响因素。方法研究对象为2002—2014年厦门市50岁以上居民,死亡数据导出至Excel 2007进行整理分析、制表及画图,用SAS 9.0软件进行非条件logistic回归分析。结果 2002—2014年厦门市50岁以上户籍人口COPD年均死亡率为51.89/10万,城市和农村居民年均死亡率男性均高于女性(P<0.05)。单因素非条件logistic回归分析结果显示,性别、城乡和年龄3个变量差异均有统计学意义(均P<0.01);多因素非条件logistic回归(逐步法)分析结果显示,性别为男性、年龄每增加5岁为COPD死亡率升高的危险因素,生活在城市为保护因素。男性COPD死亡率是女性的2.078倍(OR=2.078,P<0.01);与城市居民相比,农村居民COPD死亡率更高(OR=0.716,P<0.01);年龄每增加5岁,死于COPD的危险性增加(OR=2.328,P<0.01)。结论 COPD已成为厦门市严重的公共卫生问题,其死亡与多种因素相关,应采取综合性的预防控制措施。

[Objective]To investigate the factors influencing the mortality of chronic obstructive pulmonary disease（COPD） in Xiamen City.[Methods]The subjects included the residents over 50 years old in Xiamen City from 2002 to 2014. The mortality data were derived to excel 2007 to conduct the analysis,tab and drawing. SAS 9.0 was used to perform the non-conditional logistic regression analysis.[Results]The average annual mortality of residents over 50 years old in Xiamen City from 2002 to 2014 was51.89/lakh,and the average annual mortality rates in males were higher than those in females in both urban and rural residents（P〈0.05）. Single factor non-conditional logistic regression showed that gender,place of residence and age had statistical significance（P〈0.01）. Multi factor non-conditional logistic regression（stepwise method）revealed that male and every increase of five years in age were the risk factors of COPD,and living in the city was the protective factor. The mortality of COPD in males was 2.078 times greater than that in females（OR=2.078,P〈0.01）. The mortality of COPD in rural residents was higher than that in urban residents（OR=0.716,P〈0.01）. The mortality of COPD increased with every increase of five years in age（OR=2.328,P〈0.01）.[Conclusion]COPD has become a serious public health problem in Xiamen City. The death of COPD patients is related to various factors,and it is necessary to implement the comprehensive prevention and control measures.