孟鲁司特钠联合雾化吸入布地奈德对呼吸道合胞病毒毛细支气管炎的疗效观察

Observation on curative effect of oral Montelukast sodium tablet and budesonide for respiratory syncytial virus capillary bronchitis

目的观察口服孟鲁司特钠咀嚼片联合雾化吸入布地奈德治疗呼吸道合胞病毒毛细支气管炎的疗效。方法将临床进行病原学诊断为呼吸道合胞病毒毛细支气管炎的50例患儿随机分为两组,试验组、对照组各40例。对照组给予常规治疗加庆大霉素、地塞米松雾化,试验组给予常规治疗加普米克令舒雾化吸入联合孟鲁司特口服,观察两组临床疗效。结果试验组总有效率(92.5%)明显高于对照组总有效率(82.5%),两组比较差异有统计学意义(P﹤0.05)。试验组患儿各临床症状和体征缓解时间及住院时间均明显短于对照组,比较差异有统计学意义(P﹤0.05)。结论口服孟鲁司特联合雾化吸入普米克令舒对于治疗呼吸道合胞病毒毛细支气管炎的疗效较好,能明显缓解患者临床症状和体征,明显缩短住院时间,安全性更好,疗效肯定,有临床推广意义。

objective To observe the curative effect of Montelukast sodium chewab Ie tablet and budesonide for respiratory syncytial virus capillary bronchitis. Methods 50 cases of respiratory syncytial virus capillary bronchitis were randomly divided into two groups, experiment group and control group（n=40）. Experiment group was treated with conventional therapy and atomization of gentamycin and dexamethasone. Control group were treated with conventional therapy and Montelukast sodium chewab Ie tablet and budesonide. To observe clinical curative effect of two groups. Results Treatment group total effective rate（92.5%） is significantly higher than the control group total effective rate（82.5%）, is similar between the two groups was statistically significant（P﹤0.05）. Patients with the clinical signs and symptoms relieve time and hospital stay were significantly shorter than the control group, compare the difference was statistically significant（P﹤0.05）. Conclusion Oral Montelukast atomization inhalation of budesonide for treating respiratory syncytial virus capillary bronchitis curative effect is better, can obviously relieve the clinical symptoms and signs, significantly shorten the hospitalization time, better security, curative effect and clinical significance.