外科手术围术期输血与术后感染的临床研究

Clinical study of surgical perioperative blood transfusion and postoperative infection

目的探讨外科手术围手术期输血对术后感染的影响,为控制术后感染提供参考依据。方法选择2012年6月-2015年6月于外科进行治疗的200例围术期输血患者为研究组,另选择未进行输血的200例患者为对照组,对两组患者的术后感染率以及病原菌分布进行分析,采用SPSS18.0软件对所得的数据进行统计分析。结果观察组患者术后感染率为25.5%,明显高于对照组的2.5%,差异有统计学意义(P<0.05);观察组患者感染部位以腹、盆腔深处及手术切口为主,对照组患者感染部位为血液、肺部、手术切口等,两组患者感染部位分布比较,差异有统计学意义(P<0.05);观察组感染患者共分离出63株病原菌,其中革兰阴性菌占44.4%、革兰阳性菌占39.7%、真菌占15.9%,对照组感染患者共分离出14株病原菌,其中革兰阴性菌占42.9%、革兰阳性菌占35.7%、真菌占21.6%。结论外科手术围术期进行输血患者术后感染率明显上升。

OBJECTIVE To investigate the effects of surgery perioperative blood transfusion on postoperative infection,so as to provide a reference for the control of postoperative infection.METHODS A total of 200 cases of perioperative blood transfusion patients in the hospital surgery department from Jun.2012 to Jun.2015 were selected as observation group,another 200 cases without blood transfusion set as control group,and the postoperative infection rate and the pathogen distribution of the two groups of patients were compared.The data were analyzed by SPSS18.0.RESULTS The postoperative infection rate of observation group（25.5%）was significantly higher than that of control group（2.5%）（P〈0.05）.The main infection sites of observation group were the depths of abdomen and pelvis,and incision,and those of control group were blood,lung,and incision.There were significant differences between the two groups（P〈0.05）.Totally 63 strains of pathogenic bacteria were isolated from observation group,and gram-negative bacteria,gram-positive bacteria and fungi were accounted for 44.4%,39.7%,and 15.9%,respectively.Totally 14 strains of pathogenic bacteria were isolated from observation group,and gram-negative bacteria,gram-positive bacteria and fungi were accounted for 42.9%,35.7%,and 21.6%,respectively.CONCLUSION Perioperative blood transfusion in surgery will promote the postoperative infection in patients.