妇产科患者感染性疾病C-反应蛋白检测的临床诊断研究

Clinical diagnosis of C-reactive protein detection of patients with infectious diseases in department of obstetrics and gynecology

目的探讨C-反应蛋白(CRP)检测在妇产科感染性疾病患者中的临床诊断价值,为临床治疗妇产科感染性疾病患者提供试验依据。方法选取2014年3月-2015年3月医院妇产科收治的感染性疾病患者85例作为研究组,其中严重感染21例、中度感染35例、其他局部感染29例,并同时选取健康者83名作为对照组,比较两组间血清C-反应蛋白、红细胞沉降率、白细胞计数及中性粒细胞比值,并比较研究组患者各项检测指标阳性率及治疗后第7、14天的C-反应蛋白变化,数据采用SPSS 19.0软件进行统计分析。结果研究组患者血清C-反应蛋白、红细胞沉降率、白细胞计数及中性粒细胞比值均高于健康组;C-反应蛋白检测阳性患者80例,诊断阳性率为94.12%;研究组患者经药物治疗后,第7、14天血清C-反应蛋白水平与入院时比较,差异有统计学意义(P<0.05)。结论在妇产科感染疾病患者中使用C-反应蛋白检测,明显具有快速敏感的优点,相对于采用白细胞计数及中性粒细胞比值,判断妇产科感染有较好优势,因而在临床应用上具有较高的价值。

OBJECTIVE To investigate the clinical diagnostic value of C-reactive protein（CRP）in patients with infectious diseases in department of obstetrics and gynecology,so as to provide an experimental basis for the clinical treatment of patients with infectious diseases in department of obstetrics and gynecology.METHODS A total of 85 cases of patients with infectious diseases in department of obstetrics and gynecology from Mar.2014 to Mar.2015 were selected as study group,including 21 patients with severe infections,35 patients with moderate infections,and 29 patients with other local infections,while 83 cases of healthy persons were selected as control group.CRP level,erythrocyte sedimentation rate,leukocyte count and neutrophil ratio were compared between the two groups,and positive rates of testing indexes and changes of CRP in infected patients of study group after 7and 14 days of treatment were compared.RESULTS The CRP level,erythrocyte sedimentation rate,leukocyte count and neutrophil ratio of study group were higher than those of control group.Totally 80 cases of patients had positive CRP results,with a positive rate of 94.12%.The serum CRP level in patients of study group after 7and 14 days of treatment had significant differences with that of patients on admission（P〈0.05）.CONCLUSION Application of CRP detection in infected patients in department of obstetrics and gynecology have the advantages of fast and sensitive,and are better than diagnosis of infection by white blood cell count and neutrophil ratio in department of obstetrics and gynecology,so it has a higher value for clinical application.