摘要
目的评价内镜下扩张治疗小儿食管良性狭窄的疗效。方法71例小儿食管良性狭窄纳入回顾性分析,按狭窄病因分成3组,分别为反流性食管狭窄(A组,n=8)、先天性食管闭锁术后狭窄(B组,n=30)和化学性烧伤性食管狭窄(c组,n=33),统计总体有效率并对组间治疗情况进行对比分析。结果71例患儿共计扩张885次,总体有效率达94.37%(67/71),且3组间治疗有效率差异无统计学意义(P〉O.05)。C组平均扩张次数(14.9次/例)明显多于A组(9.1次/例,P〈O.05)和B组(10.7次/例,P〈O.05),并发症发生率亦明显高于A组(1.22%比0,P〈O.05)和B组(1.22%比0.31%,P〈O.05)。结论内镜下扩张治疗小儿食管良性狭窄总体疗效较好,但化学性烧伤性食管狭窄所需的扩张次数较多,且并发症发生率较高,属于难治性小儿食管良性狭窄。
Objective To investigate therapeutic effect of endoscope-guided bougie dilatation on children with benign esophageal stricture. Methods Data of 71 patients with benign esophageal stricture were retrospective analyzed.Patients were divided into group A (reflux stricture), B (congenital esophageal atresia stricture) and C (caustic injuries stricture), based on different causes. The expansion effectiveness and' factors of the three groups were analyzed. Results A total of 885 expansions were performed on 71 patients with the total efficacy rate 94. 37% (67/71). No statistic differences were shown in expansion effectiveness among the 3 groups; group C (14.9 times/case, P 〈 0.05 )showed more expansion frequencies than group A (9. 1 times/case,P〈0. 05)and group B ( 10. 7 times/case, P〈0. 05), more complications than group A ( 1.22% VS 0,P〈0. 05) and group B( 1.22% VS 0. 31% ,P〈0. 05). Conclusion Endoscope-guided bougie dilatation is safe and effective for childrens' benign esophageal stricture. Caustic injuries, refractory benign esophageal stricture.need more expansions and may be accompanied with more complications.
出处
《中华消化内镜杂志》
北大核心
2016年第6期375-378,共4页
Chinese Journal of Digestive Endoscopy
基金
国家高技术研究发展计划(863计划)课题(2014AA020803)
关键词
小儿食管良性狭窄
内镜下扩张
效果
危险因素
Children benign esophageal stricture
Endoscope-guided dilatation
Effectiveness
Risk factor