具有可调溶胀性能的纤维素基温敏水凝胶

Thermosensitive Cellulose-Based Hydrogels with Tunable Swelling Behavior

基于纤维素的水凝胶用途广泛,但其溶胀调控规律少见报道。文中以羟丙基甲基纤维素(HPMC)和羟乙基纤维素(HEC)为原料,以环氧氯丙烷(ECH)为交联剂,制备了系列纤维素基温敏水凝胶,研究了在温度作用下HPMC及ECH含量、p H、无机盐对水凝胶溶胀性能的影响。结果表明,制备的纤维素基水凝胶具有随温度变化可调的溶胀性能;HPMC含量越高,水凝胶收缩能力越强;ECH含量越高,水凝胶收缩能力越弱;达到溶胀平衡的水凝胶具有良好的力学性能以及p H和无机盐稳定性。

Although cellulose-based hydrogels have found numerous practical applications,the regulation of their swelling behavior was less documented. A family of thermosensitive composite cellulose-based hydrogels was prepared with hydroxypropyl methylcellulose（ HPMC） and hydroxyethyl cellulose（ HEC） as main components,epichlorohydrin（ ECH） as crosslinker. The influences of HPMC content,crosslinker dosage,p H and salt concentration on swelling behavior of the hydrogels were examined. It is found that the hydrogels display tunable swelling behavior upon variation of temperature. The higher the HPMC content,the stronger the contraction of the hydrogels; the more the ECH loading in the hydrogel,the weaker the hydrogel collapse. Moreover,the equilibrated swelling hydrogels have good mechanical performance and p H,salt tolerance.