生殖激素水平测定对早期先兆流产妊娠预后的判断价值

Predictive value of the reproductive hormone levels in threatened abortion prognosis

目的:总结在多种生殖激素在早期先兆流产妊娠预后的预测价值。方法:回顾性分析50例正常妊娠分娩者、50例先兆流产继续妊娠者及50例先兆流产难免流产者的临床资料,以正常妊娠分娩者为A组,以先兆流产继续妊娠者为B组,以先兆流产难免流产者为C组。分析三组间多种生殖激素含量差异,并探讨多种生殖激素与早期先兆流产妊娠结节的相关性。结果:三组间孕6周时P、E2及β-HCG含量存在显著差异(P<0.05),而LH、PRL及FSH无统计学差异(P>0.05)。C组P、E2及β-HCG明显低于A组及B组(P<0.05),B组P、E2及β-HCG明显低于A组(P<0.05)。同时P、E2及β-HCG含量与早期先兆流产妊娠预后存在显著的相关性(P<0.05)。结论:P、E2及β-HCG含量对早期先兆流产的妊娠预后有着显著的预测价值。

Objectives： To summarize the predictive value of reproductive hormones levels in threatened abortion prognosis. Methods： A retrospective analysis was done on clinical data of 50 cases of normal pregnancy and delivery,50 cases of threatened abortion continued pregnancy and 50 cases of threatened abortion and inevitable abortion. Normal pregnancy and delivery patients were chosen as group A; continued pregnancy patients with threatened abortion were as group B and threatened abortion inevitable abortion patients were as group C. Differences in a variety of reproductive hormones between the three groups were analyzed to explore the relevance between reproductive hormones and threatened abortion. Results： Among the three groups,at 6 weeks pregnancy,levels of P,E2 and β- HCG were significantly different（ P〈0. 05）,while LH,PRL and FSH had no significant difference（ P〈0. 05）. P,E2 and β- HCG levels in Group C were significantly lower than these in group A and group B（ P〈0. 05）. P,E2 and β- HCG levels in group B were significantly lower than these in group A（ P〈0. 05）. Meanwhile,P,E2 and β- HCG levels and threatened abortion pregnancy outcomes were in significant correlation（ P〈0. 05）. Conclusion： P,E2 and β- HCG levels have a significant predictive value on threatened abortion pregnancy prognosis.