儿童过敏性紫癜256例临床分析

Clinical analysis of 256 children with Henoch-Schonlein purpura

目的：分析儿童过敏性紫癜的临床特点。方法：对256例过敏性紫癜患儿的临床资料进行回顾性分析。结果：256例患儿中男144例,女112例,年龄2-14岁,其中小于7岁66例,7-12岁125例,12-14岁65例。151例（44.92%）患儿首发症状发生于皮肤,142例患儿（55.46%）有上呼吸道感染史,其中81例（57%）伴肾脏损害;116例（45.31%）患儿有消化道症状,其中82例（71%）伴肾脏损害;256例中103例（40.23%）有关节症状。结论：有上呼吸道感染或腹型过敏性紫癜患儿易发生肾脏损害。

Objective：To analyze the clinical features of children with Henoch-Sch？nlein purpura.Methods：The clinical data of 256 children with Henoch-Sch？nlein purpura was analyzed retrospectively.Results：Two hundred and fifty-six children（144 male and 112 female） aged from 2 to 14 years,including 66 patientsless than 7 years old,125 patients from 7 to12 years old and 65 patients from 12 to 14 years old.The earlysymptom was skin lesions in 151 patients（44.92%）.One hundred and forty-two patients（55.46%） had ahistory of upper respiratory infection,of whom 81 patients（57%） were accompanied with renal damage.Onehundred and sixteen patients had a history of abdominal manifestations,of whom 82 patients（71%） were accompanied with renal damage.One hundred and three patients（40.23%） accompanied with joint damage.Conclusion：The children with upper respiratory tract infection and abdominal symptoms are more likely tosuffer from renal damage in the children with Henoch-Sch？nlein purpura.