气管内喷雾利多卡因对甲状腺手术全麻苏醒期呛咳的抑制

Influence of Intratracheal Lidocaine Administration on Tube-induced Coughing During Anesthetic Emergence in Patients Undergoing Thyroid Surgery

目的：观察2%利多卡因气管内喷雾对甲状腺手术全麻苏醒期呛咳的影响。方法：40例ASAⅠ~Ⅱ级择期甲状腺手术患者随机分入对照组（C组）和利多卡因组（L组）,每组20例,比较两种患者气管拔管前、后不同时间段平均血压、心率、气管拔管时间及麻醉苏醒期呛咳程度及不良反应发生率。结果：与对照组比较,利多卡因组患者麻醉苏醒期呛咳程度显著减轻（P〈0.01）,血流动力学更加平稳（P〈0.01）,全麻苏醒期更少使用血管活性药物（P〈0.01）。结论：气管内喷雾利多卡因能有效抑制甲状腺手术全麻苏醒期呛咳,减轻气管拔管期间血流动力学波动,不增加不良反应。

Objective：To investigate the Influence of intratracheal lidocaine administration on tube-induced coughing during anesthetic emergence in patients undergoing thyroid surgery.Methods：A total of 40 cases of patients with ASA ofⅠ~Ⅱ undergoing thyroid surgery under general anesthesia were randomly allocated to receive intratracheal normal saline administration（group C,n=20）or 2% lidocaine administration（group L,n=20）before intubation.Coughing was assessed using a 4-point scale.The mean arterial pressure（MAP）,heart rate（HR）,the time of tracheal extubation and the incidence of side effects during anesthetic emergence were recorded.Results：Fewer patients in group L than in group C coughed（P0.01）.The hemodynamics in group L was more stable compared with group C during anesthetic emergence.The was no difference in the time of tracheal extubation and incedece of side effects.Conclusion：Intratracheal lidocaine administration before intubation was effective in attenuating tube-induced coughing and hemodynamic changes on tube-induced coughing during anesthetic emergence in patients undergoing thyroid surgery.