雾化吸入布地奈德混悬液与泼尼松治疗支气管哮喘急性发作的疗效差异

Efficacy differences of Inhalation of budesonide and prednisone in the treatment of acute attack of bronchial asthma

目的:研究雾化吸入布地奈德混悬液与泼尼松治疗支气管哮喘急性发作的疗效差异。方法:将60例支气管哮喘急性发作病例均分为两组,每组30例。对照组采取泼尼松治疗进行治疗,观察组给予雾化吸入布地奈德混悬液治疗。对比两组治疗效果和不良反应。结果:观察组患者的治疗总有效率为96.67%,明显高于对照组的76.67%,组间差异具有统计学意义(P<0.05)。观察组患者的哮喘消失时间及哮鸣音消失时间显著优于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率3.33%,显著低于对照组的23.3%,差异有统计学意义(P<0.05)。结论:在支气管哮喘急性发作患者中采取雾化吸入布地奈德混悬液治疗见效快、疗效确切,值得临床广泛应用及推广。

Objective To study of budesonide inhalation suspension prednisone difference between the treatment of bronchial asthma exacerbations effect. Method 60 cases of acute exacerbation of bronchial asthma were randomly divided into 2 groups,30 cases of each group. The control group received prednisone treatment,observation group were treated with nebulized budesonide suspension treatment. Treatment effects and adverse reactions of the two groups were observed. Results The treatment total effective rate in observation group was 96. 67%,which was significantly higher than control group 76. 67%,there was statistical significance（ P〈0. 05）. Asthma and wheeze disappearing time of observation group was better than the control group,the difference was statistically significant（ P〈0. 05）. Adverse reaction rate of observation group was 3. 33%,significantly lower than the control group 23. 3%,the difference was statistically significant（ P〈0. 05）. Conclusion In bronchial asthma exacerbations in patients with nebulized budesonide suspension treatment quick and effective,worthy of wider application and promotion.