眩晕病“内外同治”的临床观察

Clinical Research of Internal and External Treatment on Vertigo Disease

目的观察以"滋补乙癸、育阴潜阳法"为治法的固定组方中药颗粒剂,合用新型养生枕对眩晕病(原发性高血压)患者血同型半胱氨酸、尿微量白蛋白水平影响的可能机制。方法将180例眩晕病属肝肾阴虚、肝阳上亢证患者随机分为3组,各60例。对照组给予氨氯地平治疗,中药对照组在对照组基础上加用固定组方中药颗粒剂。治疗组在中药对照组基础上加用新型养生枕,3组疗程均为28 d。结果治疗后,中药对照组及治疗组均可显著降低患者各项临床症状积分级总积分(P<0.05),对照组与治疗前比较,差异无统计学意义(P>0.05);治疗组与中药对照组比较,差异有统计学意义(P<0.05)。治疗后中药对照组、治疗组均可显著降低血同型半胱氨酸、尿微量白蛋白水平(P<0.05);两组比较,差异均无统计学意义(P>0.05)。结论以"滋补乙癸、育阴潜阳法"为治则的固定组方中药颗粒剂,合用新型养生枕,可以显著改善患者的临床症状,降低患者血同型半胱氨酸、尿微量白蛋白水平。

Objective： To possible mechanism of traditional Chinese medicine granule of fixed prescription combined with health preserving pillow of new type on the blood homocysteine and urine micro albumin level of patients with vertigo disease（essential hypertension）,based on the theory Nourishing Yikui,nourishing Yin and suppressing the excessive Yang. Methods： 180 cases were randomly divided into 3 groups： the control group（amlodipine）,TCM group（amlodipine＋traditional Chinese medicine granule of fixed prescription） and the treatment group（amlodipine ＋traditional Chinese medicine granule of fixed prescription ＋health preserving pillow of new type）,60 cases in each. The treatment course lasted for 28 days. The improvement of clinical symptoms and the changes of blood homocysteine and urine micro albumin level. Results： Compared with the control group,clinical symptom scores of TCM group were dropped obviously,and the treatment group dropped most. Blood homocysteine and urine micro albumin level of TCM group dropped obviously,compared with those of the control group,which had statistical significance（P〈0.05）. There was no statistical significance between the two（P〈0.05）. Conclusion： Based on the theory Nourishing Yikui,nourishing Yin and suppressing the excessive Yang,traditional Chinese medicine granule of fixed prescription combined with health preserving pillow of new type can obviously improve the clinical symptoms and effectively decrease blood homocysteine and urine micro albumin level of the patients.