中药联合窄谱中波紫外线治疗白癜风的临床疗效观察

Clinical Observation of Curative Effect of Traditional Chinese Medicine Combined with NB-UVB in Treating Vitiligo

目的:探讨中药联合窄谱中波紫外线治疗白癜风的临床效果。方法:随机选取2014年2月至2015年12月到柳州市工人医院皮肤科门诊就诊的100例确诊为白癜风的患者,采用随机单盲分为观察组与对照组,每组各50例患者。对照组患者单纯给予中药治疗,观察组在对照组基础上联合窄谱中波紫外线治疗。对比观察2组患者经过治疗后复色率、总有效率及不良反应发生情况。结果:2组患者经过中药联合窄谱中波紫外线治疗后白癜风均有所好转,观察组患者白癜风经过中药联合窄谱中波紫外线治疗后复色率高于对照组,差异具有统计学意义(P<0.05);观察组经过中药联合窄谱中波紫外线治疗后总有效率76.1%高于对照组47.1%,差异具有统计学意义(P<0.05);2组患者在治疗过程中不良反应发生率差异不大,并且差异无统计学意义(P>0.05)。结论:中药联合窄谱中波紫外线治疗白癜风疗效显著,患者症状改善明显,并且不良反应少,值得在临床推广使用。

Abstract Objective： To observe the clinical effect of traditional Chinese medicine combined with NB-UVB in the treatment of vit- iligo. Methods：A hundred patients with vitiligo who received treatment from December to February 2014 were randomly divided into observation group and control group with 50 patients in each group. Patients in the control group treated with traditional Chi- nese medicine treatment, and patients in the observation group were additionally treated in combination of NB-UVB. The total repigmentation rate efficiency and side effects of the two groups after the treatment were compared. Results ： Vitiligo of both the two group after the treatment was improved. Repigmentation rate of patients in the observation group was higher than that of eontrol group with statistical significance difference （P 〈 0. 05）. The total efficiency of the observation group （76. 1% ） was higher than that of the control group （47. 1% ） , which showed statistically significance differenee （P 〈 0. 05 ）. The occurrence rate of adverse reactions of the two groups showed no statistically significant difference （ P 〉 0. 05 ）. Conclusion ： Traditional Chinese medicine combined with narrow spectrum UVB phototherapy in the treatment of vitiligo is significant and patients＇ symptoms were improved significantly with less adverse reactions, which is worth of clinical use.