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分流手术治疗新型隐球菌性脑膜炎的体会与文献回顾 被引量:11

Treatment of cryptococcal meningitis by use of shunting and review in literature
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摘要 目的:探讨分流手术在新型隐球菌脑膜炎患者治疗中的时机并评价其疗效。方法:回顾性分析7例采取分流手术治疗新型隐球菌脑膜炎患者的经过。结果:7例患者颅内压得到了有效的控制,相关症状明显缓解。住院及随访期间未出现与分流手术相关的并发症,未发生因分流手术造成的隐球菌播散及难治性隐球菌感染,也未发生因此导致的感染复燃。结论:分流手术可以有效缓解新型隐球菌脑膜炎所致的颅内压增高,且不对抗隐球菌的治疗产生不良影响。 Objective:To evaluate the time and effect of shunt operation on cryptococcal meningitis.Methods:A total 7 patients received shunt operation for the therapy of cryptococcal meningitis patients and the data was retrospectively analyzed.Results:Intracranial hypertension-caused symptoms were resolved immediately.There was no complication,no infection dissemination and no recrudescence of cryptococcal meningitis.Conclusion:Shunt operation is effective for intracranial hypertension caused by cryptococcal meningitis.It does not affect the antifungal treatment.
出处 《中南大学学报(医学版)》 CAS CSCD 北大核心 2016年第5期541-547,共7页 Journal of Central South University :Medical Science
关键词 分流手术 新型隐球菌脑膜炎 颅高压 脑积水 shunt cryptococcal meningitis intracranial hypertention hydrocephalus
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参考文献9

  • 1Park MK, Hospenthal DR, Bennett JE. Treatment of hydrocephalus secondary to cryptococcal meningitis by use of shunting[J]. Clin Infect Dis, 1999, 28(3): 629-633.
  • 2Liliang PC, Liang CL, Chang WN, et al. Use of ventriculoperitoneal shunts to treat uncontrollable intracranial hypertension in patients who have cryptococcaI meningitis without hydrocephalus[J]. Ciin Infect Dis, 2002, 34(12): E64-E68.
  • 3Woodworth GF, McGirt MJ, Williams MA, et al. The use of ventriculoperitoneal shunts for uncontrollable intracranial hypertension without ventriculomegally secondary to HIV-associated cryptococcal meningitis[J]. Surg Neurol, 2005, 63(6): 529-531; discussion 531-2.
  • 4Mylonakis E, Merriman NA, Rich JD, et al. Use of cerebrospinal fluid shunt for the management of elevated intracranial pressure in a patient with active AIDS-related cryptococcal meningitis[J]. Diagu Microbiol Infect Dis, 1999, 34(2): 111-114.
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  • 7Saag MS, Graybill RJ, Larsen RA, et al. Practice guidelines for the management of cryptococcal disease. Infectious Diseases Society ofAmerica [J]. Clin Infect Dis, 2000, 30(4): 710-718.
  • 8温海.隐球菌感染诊治专家共识[J].中国真菌学杂志,2010,5(2):65-68. 被引量:254
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