摘要
[目的]观察新生化颗粒联合米非司酮及米索前列醇治疗稽留流产疗效。[方法]使用随机平行对照方法,将100例住院患者按病志号抽签方法简单随机分两组。对照组50例米非司酮,25mg/次,2次/d,空腹或进食后口服,连续服用2d;第3天早晨空腹口服米索前列醇600μg。治疗组50例新生化颗粒,12g/次,3次/d,第3天米索前列醇后温水冲服;西药治疗同对照组。连续治疗5d为1疗程。观测临床症状、阴道出血时间、月经恢复情况及二次清宫、宫腔黏连、宫颈黏连、宫腔积血、宫体炎、不良反应。连续治疗2疗程,判定疗效。[结果]完全流产率治疗组优于对照组(P<0.05)。阴道流血时间与月经恢复情况治疗组优于对照组(P<0.01)。[结论]新生化颗粒联合米非司酮及米索前列醇治疗稽留流产,疗效满意,无严重不良反应,值得推广。
[Objective] Observe the efficacy of Xinshenghua granule combined with mifepristone and misoprostol in treatment of missed abortion. [Method] Using random parallel control method, 100 patients were randomly divided into two groups according to the pathography number. 50 patients In the control group were treated with mifepristone, 25 mg/times, 2 times/d, P.O. with empty stomach or after eating, continuous taking the medicine for 2 day and on the third days morning take misoprostol 600μg. 50 patients in the treatment group are giving Xinshenghua granule, 12 g/time, 3 times/d and on the third day take misoprostol with warm water. Western medicine are same as control group. Continuous treating 5 days for a course. Observation of clinical symptoms and the time of vaginal bleeding, menstrual recovery and second uterine apoxesis, uterine cavity adhesion, cervical adhesions, uterine cavity hematocele, inflammation of body of uterus, and adverse reactions. Continuous treatment for 2 courses of treatment to determine efficacy. [Result] The rate of complete abortion rate in treament group was better than control group(P〈0.05). The treatment group was better than the control group in the time of vaginal bleeding and menstrual recovery(P〈0.01). [Conclusion] Xinshenghua granule combined with mifepristone and misoprostol in treatment of missed abortion, and the results were satisfactory,no serious adverse reactions, worthy of promotion.
出处
《实用中医内科杂志》
2016年第6期70-72,共3页
Journal of Practical Traditional Chinese Internal Medicine
关键词
稽留流产
新生化颗粒
傅青主女科
生化汤
米非司酮
米索前列醇
阴道出血
月经恢复
二次清宫
宫腔黏连
宫颈黏连
宫腔积血
宫体炎
中西医结合治疗
随机平行对照研究
Missed abortion
new biological particles
Fuqingzhunvke Branch
biochemical soup
mifepristone
misoprostol
vaginal bleeding
menstruation
secondary curettage
intrauterine adhesions
cervix adhesion
uterine hemorrhage
Palace inflammation
Integrative Medicine
randomized controlled study