期刊文献+

艾滋病病毒载量检测在疾病诊断和进展评估中的应用 被引量:17

Application of viral load testing in HIV diagnosing and evaluating
原文传递
导出
摘要 本文综述了HIV病毒载量检测的意义,阐述了病毒载量检测在评估疾病进展和辅助诊断方面的应用情况,并对艾滋病防治的前景进行了展望。通过病毒载量检测可适时追踪监测HIV在人体内的复制水平、病毒动态变化,对指导艾滋病病人临床用药、评估治疗效果具有重要意义。作为一种辅助诊断技术,病毒载量检测可对抗体检测不确定的样本或新生婴儿等疑难样本进行辅助诊断,早预防、早治疗。 This article reviewed the significance HIV-1 viral load testing.The clinical application of viral load testing in HIV diagnosing and evaluating was stated,and HIV/AIDS prevention and control prospect is controllable.The level of HIV-1 can be monitored by using viral load,which is significant of guiding the use of drug and evaluating the efficacy of therapy.Viral load is used for diagnosing difficult samples as an accessory diagnostic way.It is important for early prevention and early therapy.
出处 《医学动物防制》 2016年第6期637-639,共3页 Journal of Medical Pest Control
关键词 艾滋病病毒 病毒载量检测 应用 Human immunodeficiency virus Viral load testing Application
  • 相关文献

参考文献29

  • 1YIFRU B,ASRES B.A Meta-Analysis of Risky Sexual Behaviour among Male Youth in Developing Countries[J].AIDS Research and Treatment,2015,2015:580961.
  • 2李昊雪,涛波,杨虹.HIV实验室检测技术研究进展[J].医学动物防制,2013,29(12):1353-1357. 被引量:7
  • 3HO DD,NEUMANN AU,PERELSON AS,et al.Rapid turnover of plasma virions and CD4lymphocytes in HIV-1 infection[J].Nature,1995,373(6510):123-126.
  • 4COFFIN JM.HIV population dynamics in vivo:implications for genetic variation,pathogenesis,and therapy[J].Science,1995,267(5197):483-489.
  • 5PERELSON AS,ESSUNGER P,CAO Y,et al.Decay characteristics of HIV-1-infected compartments during combination therapy[J].Nature,1997,387(6629):188-191.
  • 6AUTRAN B,CARCELAIN G,LI TS,et al.Positive effects of combined antiretroviral therapy on CD+4T cell homeostasis and function in advanced HIV disease[J].Science,1997,277(5322):112-116.
  • 7PALELLA FJ JR,DELANEY KM,MOORMAN AC,et al.Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection[J].N Engl J Med,1998,338(13):853-860.
  • 8FINZI D,BLANKSON J,SILICIANO JD,et al.Latent infection of CD+4T cells provides a mechanism for lifelong persistence of HIV-1,even in patients on effective combination therapy[J].Nat Med,1999,5(5),512-517.
  • 9FINZI D,HERMANKOVA M,PIERSON T,et al.Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy[J].Science,1997,278(5341):1295-1300.
  • 10SILICIANO JD,KAJDAS J,FINZI D,et al.Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD+4T cells[J].Nat Med,2003,9(6):727-728.

二级参考文献62

  • 1黑发欣,张启云,孙伟东,叶景荣,张琴,刘海林,卢红艳,贺雄.病毒载量应用于抗体丢失AIDS病例的诊断[J].中国艾滋病性病,2007,13(3):256-257. 被引量:9
  • 2中国疾病预防控制中心.艾滋病检测技术规范[EB/OL].[2009-09-01].http://www.edcp.org.cn/flfg/fagui/qgazbjcg.doc.
  • 3Mahe C, Kaleebu P, Ojwiya A, et al. Human immunodefieiency virus type 1 Western blot : revised diagnostic criteria with fewer indeterminate results for epidemiological studies in Africa[J]. Int J Epidemiol, 2002, 31(5) :985--990.
  • 4Uneke CJ, Alo MN, Ogbu O, et al. Western blot-indeterminate results in Nigerian patients HIV serodiagnosis., the clinical and public health implication[J]. AIDS Patient Care STDS, 2007, 21 (3):169--176.
  • 5Ravanshad M, Mahboudi F, Sabahi F, et al. Indeterminate human immunodeficiency virus western blot results in Iranian patients with discordant screening assay results[J]. Saudi Med J, 2006, 27(8):1130-1133.
  • 6Rich JD, Dickinson BP, Spaulding A, et al. Interpretation of indeterminate HIV serology results in an incarcerated population[J]. J Acquir Immune Defic Syndr Hum Retrovirol, 1998, 17 (4):376 -- 379.
  • 7Carneiro-Proietti AB, Cunha IW, Souza MM, et al. HIV-(1/2) indeterminate western blot resultst follow-up of asymptomatic blood donors in belo horizonte, minas gerais, brazil[J]. Rev Inst Med Trop Sao Paulo, 1999,41(3) : 155-- 158.
  • 8Carneiro-Proietti AB, Cunha IW, Souza MM, et al. HIV-(1/2) indeterminate western blot results: follow-up of asymptomatic blood donors in belo horizonte, minas gerais, brazil[J]. Rev Inst Med Trop Sao Paulo, 1999,41(3):155--158.
  • 9Lee JH. Follow-up investigation of indeterminate western blot results for antibody to human immunodefieieney virus type1[J]. J Formos Med Assoc, 1994,93(4):283--288.
  • 10Swaminathan S, Hanna LE, Sundaramurthi JC, et al. Prevalence and pattern of cross-reacting antibodies to HIV in patients with tuberculosis[J]. AIDS Res Hum Retroviruses, 2008, 24(7):941-946.

共引文献15

同被引文献145

引证文献17

二级引证文献78

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部