摘要
目的:确定疏肝和胃颗粒最佳水提工艺参数,为疏肝和胃颗粒水提工艺的生产提供参考。方法:以水提液蒸干残渣70%浸出物为评定指标,采用正交试验设计优化疏肝和胃颗粒水提工艺参数。结果:疏肝和胃颗粒水提最佳工艺条件为:以14倍量水提取2次,每次提取1 h。结论:该提取工艺稳定、合理,对制剂生产具有指导意义。
Objective :To provide a reference for the industrial production of water extract of shugan hewei granules by optimization the technological parameters of water extraction process. Methods :The technological parameters of water extraction process of shugan hewei granules was optimized by orthogonal experiment using 70%ethanol extract of dry residues of water extract as an indicater. Results :The process for water extraction was optizimed as extraction with 14 times of volumes of water for 2 times, 1 hour for each. Conclusion :The optimized extraction process is stable and rational, which is of a guiding signifiance in the production of the drug.
出处
《中国执业药师》
CAS
2016年第6期24-26,共3页
China Licensed Pharmacist
基金
甘肃省嘉峪关市科技计划项目(2014-38)
关键词
疏肝和胃颗粒
正交试验
水提工艺
Shugan Hewei Granules
Orthogonal Experiment
Water Extraction Process