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非经典Wnt信号通路在心脏发育和干细胞向心肌分化中的作用机制 被引量:4

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摘要 Wnt信号通路是一种哺乳动物进化保守的信号通路,在心脏发育和干细胞向心肌细胞分化中发挥重要的调控作用。经典Wnt信号通路主要调控早期心肌谱系提交,而非经典Wnt信号通路参与调控后续的心脏发育和分化。本文对非经典Wnt信号通路在心脏发育和干细胞向心肌细胞分化中的作用及其机制作一综述,以期为干细胞移植治疗缺血性心肌病提供参考策略。
出处 《生理科学进展》 CAS CSCD 北大核心 2016年第3期235-239,共5页 Progress in Physiological Sciences
基金 上海市教育委员会科研创新项目(14YZ053) 上海市自然科学基金(16ZR1437300) 上海中医药大学名师传承研究工程项目(2009120)资助课题
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