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环指蛋白43的结构、功能及其在肿瘤中的作用 被引量:1

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摘要 环指蛋白43(ring finger protein 43,RNF43)是Wnt信号通路中重要的负向调控因子之一。RNF43的异常表达、突变等改变与肿瘤的发生、发展密切相关,在临床上具有较为重要的意义。该文对RNF43的结构、功能及各项研究进展作一概述,描述其在肿瘤发生、发展进程中的作用。
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2016年第6期673-677,共5页 Chinese Journal of Clinical and Experimental Pathology
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