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心脏卵圆孔未闭致隐源性卒中的作用机制研究 被引量:1

A study on the mechanism of Cryptogenic Stroke with Patent Foramen Ovale
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摘要 目的探讨心脏卵圆孔未闭致隐源性卒中的作用机制。方法选取我院收治的伴有心脏卵圆孔未闭隐源性卒中患者50例(观察组),不伴有心脏卵圆孔未闭隐源性卒中患者50例(对照组),比较两组与隐源性卒中间的关系。结果观察组患者高血压、吸烟、高血脂发生率均低于对照组(P<0.01),心率失常、偏头痛、凝血异常发生率均高于对照组(P<0.01);观察组左室射血分数低于对照组(P<0.01),左室舒张末期内径和左室收缩末期内径均大于对照组(P<0.01);50例伴有心脏卵圆孔未闭的隐源性卒中患者中,>2 mm者42例(84.0%),≤2 mm者仅8例(16.0%)。结论心脏卵圆孔未闭引起的心率失常及凝血异常导致血栓的形成可能是导致隐源性卒中的因素,且心脏卵圆孔未闭的程度越大,隐源性卒中的发生率越大。 Objective To study the mechanism of Cryptogenic Stroke with Patent Foramen Ovale. Methods Randomly one hundred cases with cryptogenic stroke selected from our department were divided into the observation group with Patent Foramen Ovale and the control group without Patent Foramen Ovale. Results The incidence of hypertension,smoking and hyperlipidemia in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P〈0. 01). The incidence of arrhythmia,migraine and coagulation abnormalities in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P〈0. 01). For heart patent foramen ovale size≤2 mm,cryptogenic stroke incidence was 16. 0%,and for heart patent foramen ovale size 2 mm,cryptogenic stroke rate was 84. 0%,and the statistical analysis of differences was significant(P〈0. 01). Conclusion Arrhythmia,and coagulation abnormalities induced by Patent Foramen Ovale is a cause of cryptogenic stroke.
出处 《白求恩医学杂志》 2016年第3期284-285,共2页 Journal of Bethune Medical Science
关键词 心脏卵圆孔未闭 隐源性卒中 作用机制 Patent foramen ovale Cryptogenic stroke Mechanism
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