急性脑梗死抑郁症发生相关因素与预防分析

Analysis of Related Factors and Prevention of Depression in Patients With Acute Cerebral Infarction

目的分析急性脑梗死抑郁症发生相关因素与预防。方法随机选取我院2013年3月-2016年3月收治的60例急性脑梗死抑郁症患者,将其作为研究组,选取60例急性脑梗死患者,将其作为对照组,即研究组（60例）和对照组（60例）;给予研究组患者,应用丁螺环酮合并氟西汀治疗,根据汉密尔顿抑郁量表对临床患者的疗效进行评定,分析急性脑梗死抑郁症发生相关因素,并分析其预防措施。结果两组中,研究组与对照组比较,差异有统计学意义（P〈0.05）,可发现心理社会危险因素,会导致抑郁、焦虑,使患者血清IL-6、TNF-α浓度升高,形成抑郁症,研究组经心理干预及药物治疗后,患者抑郁症状得到改善,治疗前后对比临床疗效显著（P〈0.05）。结论在临床中,急性脑梗死抑郁症发生与患者神经功能缺失、性格内向、情绪不稳定、体验较多负性事件、社会支持低下有关,对患者采取药物治疗及心理干预,有助于改善患者抑郁症状,预防抑郁症形成。

Objective To analyze the related factors and prevention of depression in patients with acute cerebral infarction. Methods 60 cases of acute cerebral infarction patients with depression were randomly selected in our hospital from March 2013 to March 2016, as the study group, 60 cases of acute cerebral infarction patients were selected, as control group, that is, to study the group（60 cases） and control group（60 cases）, give the study group patients, application with buspirone combined with fluoxetine in the treatment of, according to Hamilton Depression Scale to the clinical therapeutic effects were assessed. Analysis of acute cerebral infarction depression related factors and analysis the preventive measures. Results In the two groups, the study group and the control group, there are differences（P〈0.05）, to find the psychological and social risk factors, will lead to depression, anxiety and the serum levels of IL-6 and TNF-α concentration increased, the formation of the depression, study group after mental intervention and drug therapy, depressive symptoms of patients improved, before and after the treatment to compare the clinical efficacy significantly（P〈0.05）. Conclusion In the clinical and acute cerebral infarction depression occurred and in patients with neurologic deficits, introverted, emotional instability, experience more negative events, social support, lower and of patients to take drug treatment and psychological intervention is conducive to improve depressive symptoms in patients, prevention of depression.