纳洛酮治疗老年多发脑梗死性痴呆37例

Naloxone in the Treatment of 37 Elderly Patients With Multiple Cerebral Infarction

目的探讨采用纳洛酮对老年多发脑梗死性痴呆患者加以治疗后获得的临床效果。方法选择我院2014年3月-2016年3月收治的老年多发脑梗死性痴呆患者37例作为研究的A1组（观察组）;临床接受的治疗方法为常规治疗＋纳洛酮;同期选择老年多发脑梗死性痴呆患者37例作为研究的A2组（对照组）;临床接受的治疗方法为常规治疗;对两组患者的ADL评分以及MMSE评分加以对比。结果在ADL评分以及MMSE评分两方面,A1组老年多发脑梗死性痴呆患者优于A2组（P〈0.05）。结论对老年多发脑梗死性痴呆患者采用纳洛酮药物进行治疗,可以将患者的社交能力显著提高,将患者的智能状态以及生活质量加以改善。

Objective To explore the naloxone on elderly patients with multiple cerebral infarction dementia clinical effect after treatment. Methods 37 cases of elderly patients with multiple infarction dementia patients were selected as study group A1（observation group） in our hospital from March 2014 to March 2016, clinically acceptable treatment for conventional therapy plus naloxone. At the same time, the old patients with multi infarct dementia 37 cases as study group A2（control group）, clinically acceptable treatment method for routine treatment, patients in the two groups of ADL score and MMSE score compared. Results In the ADL score and MMSE score in two aspects, A1 group of elderly patients with multiple cerebral infarction dementia than the A2 group（P〈0.05）. Conclusion For elderly patients with multiple cerebral infarction dementia patients with naloxone treatment, the patient＇s social skills can be significantly improved, the patient＇s mental state and quality of life to be improved.