油田职工阻塞性睡眠呼吸暂停综合征与代谢综合征的关系研究

Clinical study of relationship between sleep apnea syndrome and metabolic syndrome of petrol field workers

目的分析油田职工阻塞性睡眠呼吸暂停综合征（obstructivesleepapneasyndrome，OSAS）与代谢综合征（metabolicsyndrome，MS）的关系。方法选择2013年3月至2015年8月齐齐哈尔医学院第五附属医院大庆龙南医院急诊科与呼吸科因OSAS就诊的共计100例油田职工患者作为研究对象，根据OSAS的严重程度分为单纯鼾症组26例（A组），轻度OSAS组42例（B组）和中重度OSAS组32例（C组）并进一步比较各组间患者睡眠饮食情况评分和代谢相关指标之间的差异性以及进一步计算每组MS的发病率。Logistic回归分析MS的发病率与OSAS的严重程度是否具有相关性。结果A、B、C三组患者睡眠情况评分以c组（8．3±1．2）分，饮食情况评分以C组（7．6±1．4）分和MS的发病率以C组（23／32）均为最高，差异均有统计学意义（P〈0．05）；单因素与多因素Logistic回归分析MS的发病风险与OSAS的严重程度均具有相关性，多因素回归系数r=11．211[OR=9．412，95％CI：5．992～15．202]。结论油田职工OSAS病情的严重程度可明显影响患者的日常睡眠与饮食状况；随着OSAS程度加重，MS发病率增加，OSAS可能是MS发病的一个危险性因素。

Objective To analyze the relationship between obstructive sleep apnea syndrome （OSAS） and metabolic syndrome （MS） in petrol field workers. Methods A total of 100 cases of OSAS patients of petrol field workers were enrolled as the study objects from March 2013 to August 2015 in emergency and respiratory department in Daqing Longnan Hospital and were divided into three groups： simple snoring group （Group A, n = 26 ） , mild OSAS group （Group B, n = 42 ） , and severe OSAS group （ Group C, n = 32） . The comparison of dietetic status score, sleep status score and the patients with MS among 3 groups were carried out. The relationship between OSAS and MS was analyzed by using univariate and muhivariable Logistic regression analyses were used. Results In Group C, sleep status score （ 8.3 ±1.2） and dietetic status score （7.6 ±1.4） and the rates of MS （23/32） were higher than those in the other two groups （P 〈 O. 05 ） . Univariate and muhivariable Logistic regression analyses, showed OSAS was therisk factorofMS [ r=ll.211 （OR =9.412, 95% CI： 5. 992 -15. 202 ） J . Conclusions Dietetic status and sleep status were obviously influenced by OSAS in petrol field workers. The incidence of MS were more common in petrol field workersevere with OSAS and OSAS was a risk factor of MS .