摘要
SOCS3(suppressor of cytokine signaling 3)是一种细胞因子信号转导阻抑蛋白,在许多疾病的器官损伤中起着重要的调节作用,它通过对JAK/STAT信号通路的反馈调节作用抑制炎症因子的释放起到抑炎作用,现将SOCS3在重症急性胰腺炎(severe acute pancreatitis,SAP)炎症反应中的作用作一综述。
SOCS3( suppressor of cytokine signaling 3) plays an important role in regulating organs injuries of diseases,and it could inhibit cytokines from releasing by feedback regulation of JAK / STAT signal pathway. The role of SOCS3 in inflammation of severe acute pancreatitis( SAP) was summeried in this review.
出处
《胃肠病学和肝病学杂志》
CAS
2016年第6期716-718,共3页
Chinese Journal of Gastroenterology and Hepatology