铺棉灸和伐昔洛韦治疗带状疱疹临床研究

The Clinical Research into Herpes Zoster Treated with Cotton-Covered Moxibustion in Combination with Valaciclovir

目的:观察铺棉灸和伐昔洛韦治疗带状疱疹的临床疗效。方法:选取2012年3月—2014年3月本院收治的带状疱疹患者232例作为本次研究的对象,随机分为铺棉灸组和伐昔洛韦组,每组116例,分别给予铺棉灸辅助针刺治疗和伐昔洛韦治疗,观察并比较两种治疗方法的治疗效果。结果:铺棉灸组有效率93.10%,伐昔洛韦组有效率92.24%,两组有效率比较差异无统计学意义(P>0.05);铺棉灸组止疱时间与伐昔洛韦组比较,差异无统计学意义(t=1.148,P=0.252>0.05);铺棉灸组结痂时间和脱痂时间优于伐昔洛韦组(t=4.803,2.499,P均<0.05);铺棉灸组疼痛缓解时间与伐昔洛韦组比较差异无统计学意义(t=0.881,P=0.380>0.05),而疼痛持续时间显著低于伐昔洛韦组(t=6.726,P<0.01);治疗后第1个月和第2个月铺棉灸组后遗神经痛的发生情况显著少于伐昔洛韦组,差异有统计学意义(χ2=27.766,12.956,P均<0.01)。结论:铺棉灸疗法和伐昔洛韦疗法均能有效治疗带状疱疹,缓解患者的临床症状,但是铺棉灸疗法疗效更佳。

Objective： To observe the clinical curative effect of cotton-covered moxibustion in combination with valaciclovir on herpes zoster. Methods：Two hundred and thirty-two patients with herpes zoster who were treated in our hospital between March of 2012 and March of 2014 were chosen as the research objects, and randomly divided into the cotton-covered moxibustion group and the valacielovir group, with 116 cases in each group. The ones in the two groups were treated with cotton-covered moxibustion in combination with acupuncture,and valaciclovir respectively. Then the two therapies＇ clinical curative effects on herpes zoster were observed and compared. Results ： The effective rate of the cotton-covered moxibustion group was 93.10% ,while that of the valaciclovir group was 92. 10% ; And the difference between them had no statistical significance （P 〉 0.05 ）. In terms of removing herpes zoster times, the difference between the two groups had no statistical significance （ t = 1. 148, P =0. 252 〉 0.05 ）. Scat） and Slough times of the cotton-covered moxibustion group were better than those of the valaeielovir group （ t = 4.803,2. 499, all P 〈 0. 05）;In terms of pain-relieving time,the difference between the two groups had no statistical signifieance（t =0. 881 ,P = 0.380 〉 0.05 ）, while the pain duration of the cotton-covered moxibustion group was better than that of the valacielovir group （ t = 6. 726,P 〈 0.01 ）. One month and two months later after the treatment, the incidence of postherpetie neuralgia of cotton-covered moxibustion group was fewer than that of the valaciclovir group, and the difference between the two groups had statistical significance （X2 = 27. 766,12. 956 .all P 〈 0.01 ）. Conclusion ： Both cotton-covered moxibustion and valaciclovir have a remarkable clinical curative effect on herpes zoster,can relieve the patients＇ clinical symptoms, but cotton-covered moxibustion has better effect.