摘要
目的探讨N末端脑钠肽前体(NT-pro BNP)对心力衰竭预后的预测价值。方法收集2013年3月至2014年3月间来我院治疗的45例急性心衰患者以及45例慢性心衰患者,同时收集45例正常健康体检者作为对照组,对所有患者进行血清NT-pro BNP检测,评估其对心力衰竭患者预后判断的价值。结果两组心衰患者血清NT-pro BNP浓度均显著高于健康体检者(P<0.05),且NYHA分级越高的患者,其血清NT-pro BNP浓度越高(P<0.05)。经治疗后,两组心衰患者血清NT-pro BNP浓度均显著下降,与治疗前比较差异有统计学意义(P<0.05)。结论血清NT-pro BNP的检测对于快速、早期和鉴别诊断心衰患者具有重要意义,也是判断心衰治疗效果及预后的有效指标,对心衰的分级、治疗及监测也具有重要的价值。
Objective To study the predictive value of N-terminal pro-brain natriuretic peptide （NT-proBNP） for the prognosis of heart failure. Methods 45 patients with acute heart failure （AHF group）, 45 patients with chronic heart failure （CHF group） and 45 healthy subjects （control group） in our hospital from March 2013 to March 2014 were selected. The serum NT-proBNP level of patients was detected in order to evaluate its value for the prognosis of heart failure patients. Results The serum NT-proBNP levels in AHF group and CHF group were higher than those in control group （P〈0.05）; heart failure patients with higher NYHA grading had higher serum NT-proBNP levels （P 〈0.05）. After treatment, the serum NT-proBNP levels in AHF group and CHF group decreased significantly, which had statistical difference compared with that before treatment （P〈0.05）. Conclusions The detection of serum NT-proBNP has important significance for quick, early and differential diagnosis of patients with heart failure. Serum NT-proBNP is an effective indicator for estimating the treatment effect and prognosis of heart failure, which has important value for the grading, treatment and monitoring of heart failure.
出处
《临床医学工程》
2016年第6期783-784,共2页
Clinical Medicine & Engineering
