循证护理对丙型肝炎患者抗病毒治疗依从性及效果的影响分析

Impact of Evidence-Based Nursing on Antiviral Therapy Compliance and Effect of Hepatitis C Patients

目的探讨循证护理对丙型肝炎患者抗病毒治疗依从性及效果的影响。方法调查2012年1月至2015年6月我院收治的102例丙型肝炎患者的抗病毒治疗依从性和病毒学应答情况,对依从性较差者进行循证护理。结果 102例丙型肝炎患者中,66例(64.7%)患者依从性较好,36例(35.3%)患者依从性较差;依从性较好者中EVR占72.7%,PVR占27.3%;依从性较差者中EVR占8.3%,PVR占66.7%,NVR占25.0%。36例依从性较差患者给予循证护理后,28例(77.8%)患者依从性改善明显,仍有8例(22.2%)患者依从性较差;患者的依从性和病毒学应答情况明显好转(P<0.05)。结论对治疗依从性差的丙型肝炎患者,通过实施循证护理,能有效提高依从性和抗病毒治疗疗效,提高治愈率。

Objective To investigate the impact of evidence-based nursing on antiviral therapy compliance and effect of hepatitis C patients. Methods The conditions of compliance and virological response of 102 hepatitis C patients with antiviral therapy in our hospital from January 2012 to June 2015 were investigated, and patients with poor compliance were given evidence-based nursing. Results Of 102 cases, 66 cases （64.7%） had good compliance, 36 cases （35.3%） had poor compliance; EVR and PVR in patients with good compliance were 72.7% and 27.3%, respectively; EVR, PVR and NVR in patients with poor compliance were 8.3%, 66.7% and 25.0%, respectively. After 36 patients with poor compliance were given evidence-based nursing, the compliance in 28 cases （77.8%） improved significantly, with poor compliance in 8 cases （22.2%）; the compliance and virological response improved significantly （P 〈0.05）. Conclusions Evidence-based nursing can effectively improve compliance, antiviral therapy efficacy, and curative rate for hepatitis C patients with poor compliance.