奇神经节调制技术在治疗慢性非细菌性前列腺炎/慢性盆腔疼痛综合征中的临床应用与疗效观察

Efficacy of the Technique of Ganglion Impar Modulation for Treating Chronic Abacterial Prostatitis / Chronic Pelvic Pain Syndrome

目的探讨奇神经节调制技术在治疗慢性非细菌性前列腺炎/慢性盆腔疼痛综合征(CNP/CPPS)中的临床应用,并对其疗效进行观察。方法选取2013年2月—2015年3月绍兴市新昌县中医院男性科门诊符合CNP/CPPS纳入与排除标准的患者46例,按就诊先后顺序分为Ⅰ组(采用特拉唑嗪治疗)和Ⅱ组(采用奇神经节调制技术治疗),各23例,患者均治疗1个疗程。记录患者治疗前后美国国立卫生研究院慢性前列腺炎症状评分表(NIH-CPSI)评分、视觉模拟评分法(VAS)评分、前列腺按摩液(EPS)常规镜检白细胞变化情况评分;观察患者不良反应发生情况。结果治疗前两组患者NIH-CPSI评分、VAS评分、EPS常规镜检白细胞变化情况评分比较,差异均无统计学意义(P>0.05)。治疗后Ⅱ组NIH-CPSI评分、VAS评分、EPS常规镜检白细胞变化情况评分均低于Ⅰ组(P<0.05)。两组临床疗效比较,差异有统计学意义(P<0.05)。治疗期间,Ⅰ组患者均无体位性低血压及心悸情况发生,仅有1例出现轻度腹泻,另有1例出现一过性轻微头晕,未经特殊处理,3 d内自行缓解;Ⅱ组无一例发生运动/感觉功能障碍、会阴部感觉异常、排尿和/或排便功能障碍、穿刺部位感染/出血等。结论奇神经节调制技术治疗CNP/CPPS疗效显著、安全,值得临床推广应用。

Objective To evaluate the efficacy of the technique of ganglion impar modulation for treating Chronic abacterial prostatitis/ chronic pelvic pain syndrome（CNP/ CPPS）. Methods A total of 46 cases who were treated in Department of Andrology in Shaoxing Xinchang County Hospital of Traditional Chinese Medicine during Febrary 2013 to March 2015,met CNP/ CPPS inclusion and exclusion criteria,they were divided into group Ⅰ（treated with terazosin）and group Ⅱ（treated with ganglion Impar modulation technique ）equally by the sequence of seeing a doctor,all cases were treated for a treatment course. The score of the national institute health - chronic prostatits symptom index（ NIH-CPSI）,score of VAS,and score of leukocyte count in the expressed prostate secretion（EPS）were recorded before and after treatment. The adverse reactions were also observed. Results There was no significant difference in score of NIH-CPSI,score of VAS,and score of leukocyte count in the EPS between the two groups before treatment（P 〉 0. 05）. The score of NIH-CPSI,score of VAS,and score of leukocyte count in the EPS in group Ⅱ was significantly lower than that in group Ⅰ after treatment,respectively（P 〈 0. 05）. There was significant difference in clinical efficacy between the two groups（P 〈 0. 05）. During the treatment,postural hypotension and palpitation were not found among cases in group Ⅰ,one case in group Ⅰ had mild diarrhea,one case in group Ⅰ had transient slight dizziness and did not receive special treatment,symptom relieved itself in 3 days. The movement/ sensory disturbance, perineum paresthesia,voiding dysfunction,defecation obstacles and puncture site infection/ bleeding were not found among cases in group Ⅱ. Conclusion The efficacy of the technique of ganglion impar modulation is obvious for treating CNP/ CPPS,the technique is safe and worthy of being widely applied in clinic.