脂肪肝CT定量诊断与肝功能损伤的相关性研究及对临床疗效评价的价值

Relevant Research and Value in Clinical Efficacy of CT Quantitative Diagnosis of Fatty Liver for Liver Damage

目的:探讨脂肪肝CT定量诊断与患者肝功能的关系及对临床疗效评价的价值。方法:选取脂肪肝患者260例作为观察组,另取同期体检正常者40例作为对照组;测量CT定量值,对比两组间治疗前后的CT定量值差异及肝功能异常情况。结果:观察组中轻、中、重度患者分别为116、90、54例,肝功能异常率分别6.03%、14.44%、37.04%,轻度组与对照组肝功能异常率比较差异无统计学意义(P>0.05);中、重度组肝功能异常率高于对照组,差异均有统计学意义(P<0.05);治疗后,轻、中、重度组肝CT值提高,肝功能异常率降低,差异均有统计学意义(P<0.05)。结论:中、重度脂肪肝与肝功能异常有一定的相关性,CT定量诊断可评估脂肪肝的疗效。

Objective：To explore the relevance between CT quantitative diagnosis of fatty liver and liver function,and to evaluate the value of CT quantitative diagnosis in the evaluation of clinical efficacy.Method：260 patients with fatty liver were chosen as the observation group.At the same time,40 people who were healthy during physical examination were chosen as the control group.The difference of CT quantitative diagnosis and abnormal rate of liver function were compared between the two groups.Result：In the observation group,there were 116 mild cases,90 moderate cases and 54 severe cases with abnormal rate of 6.03%,14.44% and 37.04% respectively.The abnormal rate of liver function had no statistically significance difference between the mild group and the control group（P〈0.05）.The abnormal rates of liver function of the moderate group and the severe group were higher than that of the control group,the differences were statistically significant（P〈0.05）.After treatment, CT attenuation value of the mild group,the moderate group and the severe group were all increased,while the abnormal rate of liver function decreased,the differences were statistically significant（P〈0.05）.Conclusion：There are some correlations between moderate and severe fatty liver and abnormal liver function.CT quantitative diagnosis can evaluate the curative effect of fatty liver.