眼针对脑梗死半身不遂患者神经功能缺损程度和Barthel指数的影响

Impacts of eye acupuncture on neurological deficit and Barthel index in patients of infarction hemiplegia

目的:观察眼针对脑梗死半身不遂患者神经功能缺损程度和Barthel指数的影响,并探讨其作用机制。方法:将96例脑梗死半身不遂患者随机分为观察组和对照组,每组48例。对照组给予常规溶栓、抗血小板聚集等常规西药治疗,观察组在对照组治疗基础上加用眼针治疗,取双侧眼部的上焦、下焦区穴,每天1次,每周5次。观察两组患者治疗前及治疗2周后改良爱丁堡-斯堪的那维亚卒中量表(MESSS)和日常生活活动能力指数(Barthel指数,BI)的变化,比较两组间的疗效差异。比较两组治疗前及治疗2周后血浆内皮素的水平。结果:治疗后观察组与对照组有效率分别为93.8%(45/48)和79.2%(38/48),观察组有效率明显高于对照组(P<0.05)。观察组与对照组治疗后神经功能缺损程度评分分别为(13.29±1.45)分和(18.24±1.33)分,都明显低于治疗前的(28.44±1.45)分和(28.14±1.89)分(均P<0.05);治疗后组间差异有统计学意义(P<0.05)。观察组与对照组治疗后BI评分分别为(82.33±1.56)分和(63.34±2.14)分,都明显高于治疗前的(38.53±1.54)分和(38.14±2.56)分(均P<0.05),治疗后组间差异有统计学意义(P<0.05)。观察组与对照组治疗后血浆内皮素含量分别为(54.55±11.48)ng/L和(62.44±9.88)ng/L,都明显低于治疗前的(78.24±9.25)ng/L和(78.14±10.78)ng/L(均P<0.05),治疗后组间差异有统计学意义(P<0.05)。结论:眼针治疗脑梗死半身不遂能有效改善神经功能缺损程度和Barthel指数,提高综合治疗疗效,其作用机制可能与有效降低血浆内皮素含量有关。

Objective To observe the impacts of eye acupuncture on neurological deficit and Barthel index in the patients of infarction hemiplegia and explore its function mechanism.Methods Ninety-six patients of infarction hemiplegia were randomized into an observation group and a control group,48 cases in each one.In the control group,the routine western medicines such as thrombolysis and antiplatelet aggregation were used.In the observation group,on the basis of the treatment as the control group,eye acupuncture was added at Shangjiaoand Xiajiao areas bilaterally,once a day,5times a week.Separately,before treatment and after 2weeks＇ treatment the score changes of the modified Edinburgh Scandinavia stroke scale（MESSS）and the activity of daily life scale（ADL,Barthel index,BI）were observed and the efficacy was compared between the two groups.The plasma endothelin was determined and compared before and after treatment in the two groups.Results After treatment,the effective rate was 93.8%（45/48）in the observation group and was 79.2%（38/48）in the control group.The effective rate in the observation group was higher apparently than that in the control group（P〈0.05）.The scores of neurological deficit were（13.29±1.45）and（18.24±1.33）in the observation group and control group respectively after treatment,which all lower apparently than（28.44±1.45）and（28.14±1.89）before treatment（both P〈0.05）.Additionally,the difference was significant between the two groups after treatment（P〈0.05）.The scores of Barthel index were（82.33±1.56）and（63.34±2.14）in the observation group and control group respectively,which all higher apparently than（38.53±1.54）and（38.14±2.56）before treatment（both P〈0.05）,and the difference was significant between the two groups after treatment（P〈0.05）.The levels of plasma endothelin were（54.55±11.48）ng/L and（62.44±9.88）ng/L in the observation group and the control group after treatment respectively,which were all lower apparently than（78.24±9.25）ng/L and（78.14±10.78）ng/L before treatment（both P〈0.05）.Additionally,the difference was significant between the two groups after treatment（P〈0.05）.Conclusion Eye acupuncture effectively improves the neurological deficit and Brathel index in the patients of infarction hemiplegia and comprehensively improves the efficacy.The effect mechanism is possibly relevant with reducing plasma endothelin.